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Sphingo lipds
GPI Anchor
LPS Anchor
LOS Anchor
O-Glycans
N-Glycans
Example (SBA)
Example (N-Glycan)
Human milk saccarides
Blood group antigens
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ARCHITECTURE AND SHEMATIC STRUCTURE OF GLYCOSYLPHOSPHATIDYLINOSITOL
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PROTEIN
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GLYCAN CORE
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myo-INOSITOL CORE
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CORE
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LIPID
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STRUCTURE OF THE GPI CORE
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EtOHNH2-(1-1)-PO4-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)-a-D-Manp-(1-4)-a-D-GlcpN
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GPI Anchor 1
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STRUCTURE OF THE ANCHOR OF VSG
(Ferguson M.A.J.
et al The J. of Immunology, 1998, 160: 1949-1956)
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XAsp-(1-3)-EtOHNH2-(1-1)-PO4-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-2)-a-D-Manp-(1-6)+
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a-D-Manp-(1-4)-a-D-GlcpN-(1-6)-MINOSP1-(7-3)-DAcG14:0-14:0
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a-D-Galp-(1-2)-a-D-Galp-(1-6)-a-D-Galp-(1-3)+
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GPI Anchor
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STRUCTURE OF THE ANCHOR OF CD59
(Rudd et al. Biochemical Society Translation, Vol. 25 1997, 1177-1185)
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EtOHNH2-(1-1)-PO4-(1-4)+
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EtOHNH2-(1-1)-PO4-(1-4)+ |
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a-D-Manp-(1-6)-a-D-Manp-(1-4)-a-D-GlcpN-(1-6)-MINOSP1C16-(23-3)-AAcG22:4n-6-18:0
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EtOHNH2-(1-1)-PO4-(1-2)-a-D-Manp-(1-2)+ |
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b-D-GalpNAc-(1-2)+
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GPI Anchor
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STRUCTURE OF THE ANCHOR OF Rat Brain Thy-1
(Homans S.W. et al. Nature Vol. 333, 1988, 269-272) and
(Tailler D. et al. Tetrahedron Letters 40, 1999, 679-682)
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XCys-(1-3)-EtOHNH2-(1-1)-PO4-(1-6)+
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a-D-Manp-(1-2)-a-D-Manp-(1-6)+
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a-D-Manp-(1-2)+ |
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b-D-GalpNAc-(1-4)-a-D-Manp-(1-4)-a-D-GlcpN-(1-6)-MINOSP1-(7-3)-AAcG18:0-18:0
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EtOHNH2-(1-1)-PO4-(1-2)+
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GPI Anchor
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