| General Information |
| Other Name : | L-selectin, LAM-1, Mel-14 |
| Molecular Structure : | Single chain type I transmembrane glycoprotein with epidermal growth factor, C-type lectin domains and 7 N-glycosylation sites. |
| Molecular Weight : | 74-94kDa (reduced), 65kDa(unreduced) |
Functions : | Involved in leukocytes rolling and lymphocyte homing. | | Ligands : | Interacts with sialyl Lewis X (CD15s) |
| Other binding : | CD34, CD107a, CD107b |
| Expression : | By granulocytes, monocytes, T and B lymphocytes. |
| Applications : | Effective target for the treatment of chronic inflammatory disease. |
| Different Ids |
| Uniprot : | P14151 |
| OMIM : | 153240 |
| Entrez Gene : | 6402 |
| 3D-Structure : | 3CFW |
| Sequence |
| Protein : | NP_000646.2 |
| Nucleotide : | NM_000655.4 |
| Carbohydrate Microarray Data |
| CFG Data : | Glycan array Data |
| Glyaffinity Data : | Glycan array Data |
| References |
| Citations : | Pubmed |