Detail Information of CRD- CD209 :

General Information
Other Name :DC-SIGN (Dendritic Cell-Specific Intercellular adhesion molecule-3-Grabbing Non-integrin)
Molecular Structure :A type II transmembrane protein with 6 calcium binding sites, 1 N-linked glycosylation site, and 2 disulphide bonds.
Molecular Weight :44kDa
Functions :Involved in dendritic cells rolling and transendothelial migration from blood to tissues.
Ligands :Interacts with Lewis Y (CD174) on ICAM-2, Lewis X (CD15) on ICAM-3, modified LPS, mycobacterial mannosylated lipoarabibomannan (ManLAM), oligosacchride of infectious agent (M.tuberculosis, Lactobacillus species)
Other binding :HIV-type1 proteins
Expression :Expressed by immature dendritic cells and mature dendritic cells.
Applications :Used as dendritic cell receptor for many pathogens.
Different Ids
Uniprot :Q9NNX6
OMIM :604672
Entrez Gene :30835
3D-Structure :1K9I
Protein :NP_001138365.1
Nucleotide :NM_001144893.1
Carbohydrate Microarray Data
CFG Data :Glycan array Data
Glyaffinity Data :
Citations :Pubmed