Title: Ricin bound to VHH antibody V5G6
Keywords: Ribosome inactivating protein, VHH antibody, TOXIN
Source: Ricinus communis, Lama glama
Experimental method: X-RAY DIFFRACTION
Resolution: 2.301Å
Release date: 2021-08-04
Entity 1: Ricin chain A
Strand: A,D
Type: polymer
Polymer type: polypeptide(L)
Details: Glycosidase
Source: Ricinus communis (Taxonomy ID:
3988)
Entity 2: Ricin chain B
Strand: B,E
Type: polymer
Polymer type: polypeptide(L)
Details: Lectin
EC number: 3.2.2.22
Source: Ricinus communis (Taxonomy ID:
3988)
Entity 3: Anti-RON nanobody
Strand: C,F
Type: polymer
Polymer type: polypeptide(L)
Details: VHH antibody
Source: Lama glama (Taxonomy ID:
9844)
Expression system: Escherichia coli
Entity 4: alpha-L-fucopyranose-(1-3)-2-acetamido-2-deoxy-beta-D-glucopyranose
Type: branched
Entity 5: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Type: branched
Entity 6: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Type: branched
Entity 7: ZINC ION
Type: non-polymer
Entity 8: CHLORIDE ION
Type: non-polymer
Entity 9: water
Type: water
Structure entry #22772 [2 instances]
a-L-Fucp-(1-3)-b-D-GlcpNAc-(1-4)-ASN
Structure entry #548: N-Glycan fragment GlcNAc2 [2 instances]
b-D-GlcpNAc-(1-4)-b-D-GlcpNAc-(1-4)-Asn
Structure entry #551: N-Glycan fragment GlcNAc2Man1 [2 instances]
b-D-Manp-(1-4)-b-D-GlcpNAc-(1-4)-b-D-GlcpNAc-(1-4)-Asn