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Glycosciences.DB structure entry #6648:
b-D-Galp-(1-4)+
|
b-D-GlcpNAc-(1-3)-b-D-Galp
|
a-L-Fucp-(1-3)+
[][B-D-GALP]{[(3+1)][B-D-GLCPNAC]{[(3+1)][A-L-FUCP]{}[(4+1)][B-D-GALP]{}}}
RES
1b:b-dgal-HEX-1:5
2b:b-dglc-HEX-1:5
3s:n-acetyl
4b:a-lgal-HEX-1:5|6:d
5b:b-dgal-HEX-1:5
LIN
1:1o(3+1)2d
2:2d(2+1)3n
3:2o(3+1)4d
4:2o(4+1)5d
<?xml version="1.0" encoding="UTF-8"?>
<sugar version="1.0">
<residues>
<basetype id="1" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
<basetype id="2" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dglc-HEX-1:5">
<stemtype id="1" type="dglc" />
</basetype>
<substituent id="3" name="n-acetyl" />
<basetype id="4" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-lgal-HEX-1:5|6:d">
<stemtype id="1" type="lgal" />
<modification type="d" pos_one="6" />
</basetype>
<basetype id="5" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
</residues>
<linkages>
<connection id="1" parent="1" child="2">
<linkage id="1" parentType="o" childType="d">
<parent pos="3" />
<child pos="1" />
</linkage>
</connection>
<connection id="2" parent="2" child="3">
<linkage id="2" parentType="d" childType="n">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="3" parent="2" child="4">
<linkage id="3" parentType="o" childType="d">
<parent pos="3" />
<child pos="1" />
</linkage>
</connection>
<connection id="4" parent="2" child="5">
<linkage id="4" parentType="o" childType="d">
<parent pos="4" />
<child pos="1" />
</linkage>
</connection>
</linkages>
</sugar>

1 - 3 of 3 entries with matching glycan part

b-D-Galp-(1-4)+
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b-D-GlcpNAc-(1-3)-b-D-Galp-(1-1)-Methyl
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a-L-Fucp-(1-3)+
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Taxons |

b-D-Galp-(1-4)+
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b-D-GlcpNAc-(1-3)-b-D-Galp-(1-1)-<4-Trifluoroacetamidophenol>
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a-L-Fucp-(1-3)+
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Taxons |

D-Neu5Ac
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Taxons: 3 |
- Lewis X (Show) (Search Database)
Chemical Formula: | C26H45N1O20 | #C | #H | #O | #N | |
Molec. Weight: | 691 | 26 | 45 | 20 | 1 | |
# Atoms: | 92 | |||||
# Residues: | 4 | |||||
# Heavy Atoms: | 47 |
Superclasses:
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Residues:
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1 - 5 of 5 PDB entries

PDB ID 5o7u:
Crystal structure of the 7-Fluorotryptophan RSL lectin in complex with Lewis x tetrasaccharide
Description: Putative fucose-binding lectin protein
Source: Ralstonia solanacearum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.15Å
Release date: 2018-06-06
Entry features 4 distinct glycan structures [4 instances].

PDB ID 5o7w:
Crystal structure of the 4-FLUORO RSL lectin in complex with Lewis x tetrasaccharide
Description: Fucose-binding lectin protein
Source: Ralstonia solanacearum
Experimental method: X-RAY DIFFRACTION
Resolution: 1.35Å
Release date: 2018-06-06
Entry features 3 distinct glycan structures [3 instances].

PDB ID 5a70:
Structure of the LecB lectin from Pseudomonas aeruginosa strain PA14 in complex with lewis x tetrasaccharide
Description: LECB
Source: PSEUDOMONAS AERUGINOSA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6Å
Release date: 2016-07-27
Entry features 1 distinct glycan structures [4 instances].

PDB ID 3zw1:
Structure of Bambl lectine in complex with lewix x antigen
Description: BAMBL LECTIN
Source: BURKHOLDERIA AMBIFARIA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6Å
Release date: 2011-11-16
Entry features 2 distinct glycan structures [4 instances].

PDB ID 1sl5:
Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with LNFP III (Dextra L504).
Description: mDC-SIGN1B type I isoform
Source: Homo sapiens
Experimental method: X-RAY DIFFRACTION
Resolution: 1.8Å
Release date: 2004-06-15
Entry features 1 distinct glycan structures [1 instances].

Map ID: 8362
Disaccharide Fragment: a-L-Fucp-(1-3)-b-D-GlcpNAc
Linkage Path: 33
Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns

Map ID: 8363
Disaccharide Fragment: b-D-Galp-(1-4)-b-D-GlcpNAc
Linkage Path: 34
Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns

Map ID: 8364
Disaccharide Fragment: b-D-GlcpNAc-(1-3)-b-D-Galp
Linkage Path: 3
Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns
1 - 5 of 5 literature references

Reference #20857
Sletmoen M; Gerken TA; Stokke BT; Burchell J; Brewer CF
Tn and STn are members of a family of carbohydrate tumor antigens that possess carbohydrate-carbohydrate interactions.
Published 2018 in Glycobiology, 28: 437-442
Reference contains 13 structures

Reference #7889
Ito K; Handa K; Hakomori SI
Species-specific expression of sialosyl-Lex on polymorphonuclear leukocytes (PMN), in relation to selectin-dependent PMN responses
Published 1994 in Glycoconj J, 11: 232-237
Reference contains 5 structures

Reference #8085
Nakayama J; Ota H; Katsuyama T; Kanai M; Taki T; Hirabayashi Y; Suzuki Y
Immunohistochemical demonstration of glycoconjugates bearing the type 2 chain-backbone structure in human fetal, normal and neoplastic gastrointestinal tract
Published 1992 in Histochemistry, 97: 303-310
Reference contains 8 structures

Reference #3165
Nakasaki H; Mitomi T; Noto T; Ogoshi K; Hanaue H; Tanaka Y; Makuuchi H; Clausen H; Hakomori S
Mosaicism in the expression of tumor-associated carbohydrate antigens in human colonic and gastric cancers
Published 1989 in Cancer Res, 49: 3662-3669
Reference contains 4 structures

Reference #11808
Kaieda H; Yamada K; Yamawaki N
Induced immune cells against cancer
Published 1986 in Jpn Kokai Tokkyo Koho, 0: 1-5
Reference contains 1 structure
1 - 2 of 2 literature references from PDB entries

Reference #18634
Topin J; Arnaud J; Sarkar A; Audfray A; Gillon E; Perez S; Jamet H; Varrot A; Imberty A; Thomas A
Deciphering the glycan preference of bacterial lectins by glycan array and molecular docking with validation by microcalorimetry and crystallography.
Published 2013 in PLoS ONE, 8: e71149

Reference #16468
Guo Y; Feinberg H; Conroy E; Mitchell DA; Alvarez R; Blixt O; Taylor ME; Weis WI; Drickamer K
Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR.
Published 2004 in Nat. Struct. Mol. Biol., 11: 591-8
NCBI Taxonomy ID | Scientific Name |
9606 | Homo sapiens |
Consortium for Functional Glycomics (CFG):
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