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Glycosciences.DB structure entry #5131: Lewis D Trisaccharide / Blood Group H antigen, type 1 (beta-anomeric form)
a-L-Fucp-(1-2)-b-D-Galp-(1-3)-b-D-GlcpNAc
[][B-D-GLCPNAC]{[(3+1)][B-D-GALP]{[(2+1)][A-L-FUCP]{}}}
RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-lgal-HEX-1:5|6:d
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3o(2+1)4d
<?xml version="1.0" encoding="UTF-8"?>
<sugar version="1.0">
<residues>
<basetype id="1" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dglc-HEX-1:5">
<stemtype id="1" type="dglc" />
</basetype>
<substituent id="2" name="n-acetyl" />
<basetype id="3" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
<basetype id="4" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-lgal-HEX-1:5|6:d">
<stemtype id="1" type="lgal" />
<modification type="d" pos_one="6" />
</basetype>
</residues>
<linkages>
<connection id="1" parent="1" child="2">
<linkage id="1" parentType="d" childType="n">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="2" parent="1" child="3">
<linkage id="2" parentType="o" childType="d">
<parent pos="3" />
<child pos="1" />
</linkage>
</connection>
<connection id="3" parent="3" child="4">
<linkage id="3" parentType="o" childType="d">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
</linkages>
</sugar>

1 - 5 of 9 entries with matching glycan part

a-L-Fucp-(1-2)-b-D-Galp-(1-3)-b-D-GlcpNAc-(1-9)-9-hydroxy-Nonanoate-(1-1)-Methyl
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Taxons: 1 |

a-L-Fucp-(1-2)-b-D-Galp-(1-3)-b-D-GlcpNAc-(1-O)-<BSA>
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Taxons |

a-L-Fucp-(1-2)-b-D-Galp-(1-3)-b-D-GlcpNAc-(1-1)-<4-nitrophenol>
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Taxons |

a-L-Fucp-(1-2)-b-D-Galp-(1-3)-b-D-GlcpNAc-(1-7)-benzyl
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Taxons |

a-L-Fucp-(1-2)-b-D-Galp-(1-3)-b-D-GlcpNAc-(1-1)-Methyl
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Taxons: 1 |
- Blood Group H Antigen (Show) (Search Database)
- Neo-Lactosamine (Show) (Search Database)
- Lewis D
- LeD
- Le(D)
- Le-D
- Lewis-D
- Blood group H Type 1
- BGH type 1
- H Antigen Type 1
- Type 1 H antigen
- ABO blood group antigen
Chemical Formula: | C20H35N1O15 | #C | #H | #O | #N | |
Molec. Weight: | 529 | 20 | 35 | 15 | 1 | |
# Atoms: | 71 | |||||
# Residues: | 3 | |||||
# Heavy Atoms: | 36 |
Superclasses:
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Residues:
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1 - 2 of 2 PDB entries

PDB ID 6ha0:
Unraveling the role of the secretor antigen in human rotavirus attachment to histo-blood group antigens
Description: Outer capsid protein VP4
Source: Rotavirus A
Experimental method: X-RAY DIFFRACTION
Resolution: 1.85Å
Release date: 2019-06-12
Entry features 1 distinct glycan structures [1 instances].

PDB ID 3zw2:
Structure of the lectine Bambl from Burkholderia ambifaria in complex with blood group H type 1 tetrasaccharide
Description: BAMBL LECTIN
Source: BURKHOLDERIA AMBIFARIA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6Å
Release date: 2011-11-16
Entry features 3 distinct glycan structures [6 instances].

Map ID: 8847
Disaccharide Fragment: a-L-Fucp-(1-2)-b-D-Galp
Linkage Path: 32
Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns

Map ID: 8848
Disaccharide Fragment: b-D-Galp-(1-3)-b-D-GlcpNAc
Linkage Path: 3
Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns
1 - 5 of 24 literature references

Reference #21957
Montesino B; Steenackers A; Lozano JM; Young GD; Hu N; Sackstein R; Chandler KB
Identification of α1,2-fucosylated signaling and adhesion molecules in head and neck squamous cell carcinoma.
Published 2022 in Glycobiology, 32: 441-455
Reference contains 4 structures

Reference #22043
Bleuler-Martinez S; Varrot A; Olieric V; Schubert M; Vogt E; Fetz C; Wohlschlager T; Plaza DF; Wälti M; Duport Y; Capitani G; Aebi M; Künzler M
Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity.
Published 2022 in Glycobiology, 32: 600-615
Reference contains 27 structures

Reference #21691
Nguyen L; McCord KA; Bui DT; Bouwman KM; Kitova EN; Elaish M; Kumawat D; Daskhan GC; Tomris I; Han L; Chopra P; Yang TJ; Willows SD; Mason AL; Mahal LK; Lowary TL; West LJ; Hsu SD; Hobman T; Tompkins SM; Boons GJ; de Vries RP; Macauley MS; Klassen JS
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.
Published 2022 in Nat Chem Biol, 18: 81-90
Reference contains 33 structures

Reference #21992
Blenda AV; Kamili NA; Wu SC; Abel WF; Ayona D; Gerner-Smidt C; Ho AD; Benian GM; Cummings RD; Arthur CM; Stowell SR
Galectin-9 recognizes and exhibits antimicrobial activity toward microbes expressing blood group-like antigens.
Published 2022 in J Biol Chem, 298: 101704
Reference contains 42 structures

Reference #22000
Sojitra M; Sarkar S; Maghera J; Rodrigues E; Carpenter EJ; Seth S; Ferrer Vinals D; Bennett NJ; Reddy R; Khalil A; Xue X; Bell MR; Zheng RB; Zhang P; Nycholat C; Bailey JJ; Ling CC; Lowary TL; Paulson JC; Macauley MS; Derda R
Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage.
Published 2021 in Nat Chem Biol, 17: 806-816
Reference contains 65 structures
1 - 1 of 1 literature references from PDB entries

Reference #18053
Audfray A; Claudinon J; Abounit S; Ruvoën-Clouet N; Larson G; Smith DF; Wimmerová M; Le Pendu J; Römer W; Varrot A; Imberty A
Fucose-binding lectin from opportunistic pathogen Burkholderia ambifaria binds to both plant and human oligosaccharidic epitopes.
Published 2012 in J. Biol. Chem., 287: 4335-47
Consortium for Functional Glycomics (CFG):
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