- ☰
- Add title
- Add keywords
- Add publication
- Leave comment
Glycosciences.DB structure entry #5065:
a-D-GalpNAc-(1-3)+
|
b-D-Galp-(1-3)-b-D-GlcpNAc
|
a-L-Fucp-(1-2)+
[][B-D-GLCPNAC]{[(3+1)][B-D-GALP]{[(2+1)][A-L-FUCP]{}[(3+1)][A-D-GALPNAC]{}}}
RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-lgal-HEX-1:5|6:d
5b:a-dgal-HEX-1:5
6s:n-acetyl
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3o(2+1)4d
4:3o(3+1)5d
5:5d(2+1)6n
<?xml version="1.0" encoding="UTF-8"?>
<sugar version="1.0">
<residues>
<basetype id="1" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dglc-HEX-1:5">
<stemtype id="1" type="dglc" />
</basetype>
<substituent id="2" name="n-acetyl" />
<basetype id="3" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
<basetype id="4" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-lgal-HEX-1:5|6:d">
<stemtype id="1" type="lgal" />
<modification type="d" pos_one="6" />
</basetype>
<basetype id="5" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
<substituent id="6" name="n-acetyl" />
</residues>
<linkages>
<connection id="1" parent="1" child="2">
<linkage id="1" parentType="d" childType="n">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="2" parent="1" child="3">
<linkage id="2" parentType="o" childType="d">
<parent pos="3" />
<child pos="1" />
</linkage>
</connection>
<connection id="3" parent="3" child="4">
<linkage id="3" parentType="o" childType="d">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="4" parent="3" child="5">
<linkage id="4" parentType="o" childType="d">
<parent pos="3" />
<child pos="1" />
</linkage>
</connection>
<connection id="5" parent="5" child="6">
<linkage id="5" parentType="d" childType="n">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
</linkages>
</sugar>
3D Structure Model1 - 3 of 3 entries with matching glycan part
Structure entry #5996:
a-D-GalpNAc-(1-3)+
|
b-D-Galp-(1-3)-b-D-GlcpNAc-(1-1)-Methyl
|
a-L-Fucp-(1-2)+
 |
 |
 |
 : 3 |
 |
Taxons |
Structure entry #6493:
a-D-GalpNAc-(1-3)+
|
b-D-Galp-(1-3)-b-D-GlcpNAc-(1-9)-9-hydroxy-Nonanoate-(1-1)-Methyl
|
a-L-Fucp-(1-2)+
|
|
|
: 2 |
|
Taxons |
Structure entry #19145:
a-D-GalpNAc-(1-3)+
|
b-D-Galp-(1-3/4)-b-D-GlcpNAc
|
a-L-Fucp-(1-2)+
 |
|
|
: 2 |
|
Taxons: 1 |
- Blood Group A Antigen (Show) (Search Database)
- Neo-Lactosamine (Show) (Search Database)
| Chemical Formula: | C28H48N2O20 | #C | #H | #O | #N | |
| Molec. Weight: | 732 | 28 | 48 | 20 | 2 | |
| # Atoms: | 98 | |||||
| # Residues: | 4 | |||||
| # Heavy Atoms: | 50 | |||||
Superclasses:
|
Residues:
|
||||||||||||||||||
PDB references: 41 - 4 of 4 PDB entries
PDB ID 4d6f:
Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the blood group A-tetrasaccharide (E558A, X01 mutant)
Description: GLYCOSIDE HYDROLASE (E.C.3.2.1.102)
Source: STREPTOCOCCUS PNEUMONIAE
Experimental method: X-RAY DIFFRACTION
Resolution: 2.03Å
Release date: 2014-11-26
Entry features 1 distinct glycan structures [1 instances].
PDB ID 4d6h:
Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 1 blood group A-tetrasaccharide (E558A X02 mutant)
Description: GLYCOSIDE HYDROLASE (E.C.3.2.1.102)
Source: STREPTOCOCCUS PNEUMONIAE
Experimental method: X-RAY DIFFRACTION
Resolution: 1.65Å
Release date: 2014-11-26
Entry features 1 distinct glycan structures [1 instances].
PDB ID 4d6i:
Crystal structure of a family 98 glycoside hydrolase catalytic module (Sp3GH98) in complex with the type 1 blood group A-tetrasaccharide (E558A L19 mutant)
Description: GLYCOSIDE HYDROLASE (E.C.3.2.1.102)
Source: STREPTOCOCCUS PNEUMONIAE
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99Å
Release date: 2014-11-26
Entry features 1 distinct glycan structures [1 instances].
PDB ID 3asp:
Crystal structure of P domain from Norovirus Funabashi258 stain in the complex with A-antigen
Description: Capsid protein
Source: Norwalk-like virus
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6Å
Release date: 2012-01-25
Entry features 1 distinct glycan structures [2 instances].
Conformational maps: 3
Map ID: 8539
Disaccharide Fragment: a-L-Fucp-(1-2)-b-D-Galp
Linkage Path: 32
Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns
Map ID: 8540
Disaccharide Fragment: b-D-Galp-(1-3)-b-D-GlcpNAc
Linkage Path: 3
Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns
Map ID: 8541
Disaccharide Fragment: a-D-GalpNAc-(1-3)-b-D-Galp
Linkage Path: 33
Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns
Literature references: 111 - 5 of 11 literature references
Reference #21992
Blenda AV; Kamili NA; Wu SC; Abel WF; Ayona D; Gerner-Smidt C; Ho AD; Benian GM; Cummings RD; Arthur CM; Stowell SR
Galectin-9 recognizes and exhibits antimicrobial activity toward microbes expressing blood group-like antigens.
Published 2022 in J Biol Chem, 298: 101704
Reference contains 42 structures
Reference #21691
Nguyen L; McCord KA; Bui DT; Bouwman KM; Kitova EN; Elaish M; Kumawat D; Daskhan GC; Tomris I; Han L; Chopra P; Yang TJ; Willows SD; Mason AL; Mahal LK; Lowary TL; West LJ; Hsu SD; Hobman T; Tompkins SM; Boons GJ; de Vries RP; Macauley MS; Klassen JS
Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.
Published 2022 in Nat Chem Biol, 18: 81-90
Reference contains 33 structures
Reference #22043
Bleuler-Martinez S; Varrot A; Olieric V; Schubert M; Vogt E; Fetz C; Wohlschlager T; Plaza DF; Wälti M; Duport Y; Capitani G; Aebi M; Künzler M
Structure-function relationship of a novel fucoside-binding fruiting body lectin from Coprinopsis cinerea exhibiting nematotoxic activity.
Published 2022 in Glycobiology, 32: 600-615
Reference contains 27 structures
Reference #21311
Rahfeld P; Withers SG
Towards universal donor blood: enzymatic conversion of A and B to O type.
Published 2019 in J. Biol. Chem., :
Reference contains 17 structures
Reference #21173
Buettner MJ; Shah SR; Saeui CT; Ariss R; Yarema KJ
Improving Immunotherapy Through Glycodesign.
Published 2018 in Front Immunol, 9: 2485
Reference contains 42 structures
1 - 2 of 2 literature references from PDB entries
Reference #19172
Kwan DH; Constantinescu I; Chapanian R; Higgins MA; Kötzler MP; Samain E; Boraston AB; Kizhakkedathu JN; Withers SG
Toward Efficient Enzymes for the Generation of Universal Blood through Structure-Guided Directed Evolution.
Published 2015 in J. Am. Chem. Soc., 137: 5695-705
Reference #18241
Kubota T; Kumagai A; Ito H; Furukawa S; Someya Y; Takeda N; Ishii K; Wakita T; Narimatsu H; Shirato H
Structural basis for the recognition of Lewis antigens by genogroup I norovirus.
Published 2012 in J. Virol., 86: 11138-50
×
Add title to glycan structure entry:
×
Add keyword to glycan structure entry:
×
Add publication to glycan structure entry:
×