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Glycosciences.DB structure entry #437: Glycosphingolipid GD1b


    b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+
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                               b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide
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 a-D-Neup5Ac-(2-8)-a-D-Neup5Ac-(2-3)+

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Corresponding entries: 2

1 - 2 of 2 entries with matching glycan part

Structure entry #22440:

b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)-b-D-Galp-(1-4)-b-D-Glcp | a-D-Neup5Ac-(2-8)-a-D-Neup5Ac-(2-3)+

: 9

Taxons

Structure entry #25119:

a-D-Neup5Ac-(2-8)-a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Cer | b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+

no Ref

Taxons

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Motifs: 2

GSL core, ganglio-type (Show) (Search Database)
GD1b (Show) (Search Database)

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Trivial names

GD1b
II3(Neu5Ac)2Gg4Cer

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Keywords

glycosphingolipid

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General Structure Data

Chemical Formula:	C₈₁H₁₄₂N₄O₃₉	#C	#H	#O	#N
Molec. Weight:	1795	81	142	39	4
# Atoms:	266
# Residues:	7
# Heavy Atoms:	124

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Composition

Superclasses:

Neu		Hex
NeuAc	2	Hex	3
		HexNAc	1

Residues:

Residue	Count
A-D-NEUP5AC	2
B-D-GALP	2
B-D-GALPNAC	1
B-D-GLCP	1
CERAMIDE	1

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NMR Carbon Chemical Shift Info

MHz	0
Temperature	0
Solvent	D2O
Residue	Linkage	Carbon	PPM	JFrom	JTo	Hz	Note
b-D-Glcp	4,1	C1	103.40			0
b-D-Glcp	4,1	C2	73.50			0
b-D-Glcp	4,1	C3	75.10			0
b-D-Glcp	4,1	C4	79.40			0
b-D-Glcp	4,1	C5	75.70			0
b-D-Glcp	4,1	C6	61.00			0
b-D-Galp	4,4,1	C1	103.40			0
b-D-Galp	4,4,1	C2	70.70			0
b-D-Galp	4,4,1	C3	75.10			0
b-D-Galp	4,4,1	C4	78.90			0
b-D-Galp	4,4,1	C5	75.10			0
b-D-Galp	4,4,1	C6	61.80			0
b-D-GalpNAc	4,4,4,1	C1	103.40			0
b-D-GalpNAc	4,4,4,1	C2	53.30			0
b-D-GalpNAc	4,4,4,1	C3	81.20			0
b-D-GalpNAc	4,4,4,1	C4	68.90			0
b-D-GalpNAc	4,4,4,1	C5	75.70			0
b-D-GalpNAc	4,4,4,1	C6	61.50			0
b-D-Galp	3,4,4,4,1	C1	105.50			0
b-D-Galp	3,4,4,4,1	C2	71.60			0
b-D-Galp	3,4,4,4,1	C3	73.50			0
b-D-Galp	3,4,4,4,1	C4	68.20			0
b-D-Galp	3,4,4,4,1	C5	75.70			0
b-D-Galp	3,4,4,4,1	C6	61.80			0
a-D-Neup5Ac	3,4,4,1	C1	174.20			0
a-D-Neup5Ac	3,4,4,1	C2	102.00			0
a-D-Neup5Ac	3,4,4,1	C3	39.40			0
a-D-Neup5Ac	3,4,4,1	C4	69.20			0
a-D-Neup5Ac	3,4,4,1	C5	52.20			0
a-D-Neup5Ac	3,4,4,1	C6	73.50			0
a-D-Neup5Ac	3,4,4,1	C7	69.20			0
a-D-Neup5Ac	3,4,4,1	C8	77.70			0
a-D-Neup5Ac	3,4,4,1	C9	62.40			0
a-D-Neup5Ac	8,3,4,4,1	C1	174.20			0
a-D-Neup5Ac	8,3,4,4,1	C2	101.40			0
a-D-Neup5Ac	8,3,4,4,1	C3	41.40			0
a-D-Neup5Ac	8,3,4,4,1	C4	69.20			0
a-D-Neup5Ac	8,3,4,4,1	C5	52.80			0
a-D-Neup5Ac	8,3,4,4,1	C6	73.50			0
a-D-Neup5Ac	8,3,4,4,1	C7	69.20			0
a-D-Neup5Ac	8,3,4,4,1	C8	72.60			0
a-D-Neup5Ac	8,3,4,4,1	C9	63.60			0

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Literature references: 287

1 - 5 of 287 literature references

Reference #21973

Inokuchi JI; Nagafuku M

Gangliosides in T cell development and function of mice.

Published 2022 in Glycoconj J, 39: 229-238

Reference contains 9 structures

Reference #21969

Liang YJ

Glycosphingolipids in human embryonic stem cells and breast cancer stem cells, and potential cancer therapy strategies based on their structures and functions.

Published 2022 in Glycoconj J, 39: 177-195

Reference contains 21 structures

Reference #21955

Zalem D; Juhás M; Terrinoni M; King-Lyons N; Lebens M; Varrot A; Connell TD; Teneberg S

Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.

Published 2022 in Glycobiology, 32: 391-403

Reference contains 29 structures

Reference #21963

Wallom KL; Fernández-Suárez ME; Priestman DA; Te Vruchte D; Huebecker M; Hallett PJ; Isacson O; Platt FM

Glycosphingolipid metabolism and its role in ageing and Parkinson's disease.

Published 2022 in Glycoconj J, 39: 39-53

Reference contains 6 structures

Reference #21874

Timur ZK; Inci OK; Demir SA; Seyrantepe V

Sialidase neu4 deficiency is associated with neuroinflammation in mice.

Published 2021 in Glycoconj J, 38: 649-667

Reference contains 5 structures

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Taxonomy: 15

NCBI Taxonomy ID	Scientific Name
9913	Bos taurus
9615	Canis familiaris
7957	Carassius auratus
8113	Cichlidae
10026	Cricetinae
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
10090	Mus musculus
9986	Oryctolagus cuniculus
9557	Papio hamadryas
10114	Rattus
9376	Soricidae
9823	Sus scrofa
9739	Tursiops truncatus

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Crosslinks: 1

GlycoEpitope DB:

EP0059

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Glycosciences.DB structure entry #437: Glycosphingolipid GD1b

1 - 2 of 2 entries with matching glycan part

1 - 5 of 287 literature references

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