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Glycosciences.DB structure entry #436: Glycosphingolipid GD1a


 a-D-Neup5Ac-(2-3)-b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+
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                                              b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide
                                                   |
                                  a-D-Neup5Ac-(2-3)+

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Corresponding entries: 4

1 - 4 of 4 entries with matching glycan part

Structure entry #2877:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-hexyl | a-D-Neup5Ac-(2-3)+

: 1

Taxons

Structure entry #3949:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol | a-D-Neup5Ac-(2-3)+

: 1

Taxons

Structure entry #3950:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Eicos-4E-en-1,3S-diol | a-D-Neup5Ac-(2-3)+

: 1

Taxons

Structure entry #22439:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)-b-D-Galp-(1-4)-b-D-Glcp | a-D-Neup5Ac-(2-3)+

Taxons

GSL core, ganglio-type (Show) (Search Database)
GD1a (Show) (Search Database)

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Trivial names

GD1a
IV3Neu5AcII3Neu5AcGg4Cer

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Keywords

glycosphingolipid

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General Structure Data

Chemical Formula:	C₈₁H₁₄₂N₄O₃₉	#C	#H	#O	#N
Molec. Weight:	1795	81	142	39	4
# Atoms:	266
# Residues:	7
# Heavy Atoms:	124

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Composition

Superclasses:

Neu		Hex
NeuAc	2	Hex	3
		HexNAc	1

Residues:

Residue	Count
A-D-NEUP5AC	2
B-D-GALP	2
B-D-GALPNAC	1
B-D-GLCP	1
CERAMIDE	1

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NMR Carbon Chemical Shift Info

MHz	0
Temperature	0
Solvent	D2O
Residue	Linkage	Carbon	PPM	JFrom	JTo	Hz	Note
b-D-Glcp	4,1	C1	103.50			0
b-D-Glcp	4,1	C2	73.80			0
b-D-Glcp	4,1	C3	75.20			0
b-D-Glcp	4,1	C4	79.90			0
b-D-Glcp	4,1	C5	75.50			0
b-D-Glcp	4,1	C6	61.00			0
b-D-Galp	4,4,1	C1	103.50			0
b-D-Galp	4,4,1	C2	70.80			0
b-D-Galp	4,4,1	C3	75.20			0
b-D-Galp	4,4,1	C4	78.30			0
b-D-Galp	4,4,1	C5	75.20			0
b-D-Galp	4,4,1	C6	61.90			0
b-D-GalpNAc	4,4,4,1	C1	103.50			0
b-D-GalpNAc	4,4,4,1	C2	52.90			0
b-D-GalpNAc	4,4,4,1	C3	81.80			0
b-D-GalpNAc	4,4,4,1	C4	68.50			0
b-D-GalpNAc	4,4,4,1	C5	75.50			0
b-D-GalpNAc	4,4,4,1	C6	61.50			0
b-D-Galp	3,4,4,4,1	C1	105.40			0
b-D-Galp	3,4,4,4,1	C2	71.40			0
b-D-Galp	3,4,4,4,1	C3	76.50			0
b-D-Galp	3,4,4,4,1	C4	69.20			0
b-D-Galp	3,4,4,4,1	C5	75.50			0
b-D-Galp	3,4,4,4,1	C6	61.90			0
a-D-Neup5Ac	3,3,4,4,4,1	C1	174.90			0
a-D-Neup5Ac	3,3,4,4,4,1	C2	100.70			0
a-D-Neup5Ac	3,3,4,4,4,1	C3	40.70			0
a-D-Neup5Ac	3,3,4,4,4,1	C4	69.20			0
a-D-Neup5Ac	3,3,4,4,4,1	C5	52.90			0
a-D-Neup5Ac	3,3,4,4,4,1	C6	73.80			0
a-D-Neup5Ac	3,3,4,4,4,1	C7	69.20			0
a-D-Neup5Ac	3,3,4,4,4,1	C8	72.70			0
a-D-Neup5Ac	3,3,4,4,4,1	C9	63.60			0
a-D-Neup5Ac	3,4,4,1	C1	174.80			0
a-D-Neup5Ac	3,4,4,1	C2	102.60			0
a-D-Neup5Ac	3,4,4,1	C3	38.00			0
a-D-Neup5Ac	3,4,4,1	C4	69.20			0
a-D-Neup5Ac	3,4,4,1	C5	51.90			0
a-D-Neup5Ac	3,4,4,1	C6	73.80			0
a-D-Neup5Ac	3,4,4,1	C7	69.20			0
a-D-Neup5Ac	3,4,4,1	C8	73.00			0
a-D-Neup5Ac	3,4,4,1	C9	63.60			0

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Literature references: 374

1 - 5 of 374 literature references

Reference #21965

Ledeen R; Chowdhury S; Lu ZH; Chakraborty M; Wu G

Systemic deficiency of GM1 ganglioside in Parkinson's disease tissues and its relation to the disease etiology.

Published 2022 in Glycoconj J, 39: 75-82

Reference contains 2 structures

Reference #21970

He X; Guan F; Lei L

Structure and function of glycosphingolipids on small extracellular vesicles.

Published 2022 in Glycoconj J, 39: 197-205

Reference contains 8 structures

Reference #21955

Zalem D; Juhás M; Terrinoni M; King-Lyons N; Lebens M; Varrot A; Connell TD; Teneberg S

Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.

Published 2022 in Glycobiology, 32: 391-403

Reference contains 29 structures

Reference #21968

Furukawa K; Ohmi Y; Hamamura K; Kondo Y; Ohkawa Y; Kaneko K; Hashimoto N; Yesmin F; Bhuiyan RH; Tajima O; Furukawa K

Signaling domains of cancer-associated glycolipids.

Published 2022 in Glycoconj J, 39: 145-155

Reference contains 11 structures

Reference #21691

Nguyen L; McCord KA; Bui DT; Bouwman KM; Kitova EN; Elaish M; Kumawat D; Daskhan GC; Tomris I; Han L; Chopra P; Yang TJ; Willows SD; Mason AL; Mahal LK; Lowary TL; West LJ; Hsu SD; Hobman T; Tompkins SM; Boons GJ; de Vries RP; Macauley MS; Klassen JS

Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.

Published 2022 in Nat Chem Biol, 18: 81-90

Reference contains 33 structures

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Taxonomy: 18

NCBI Taxonomy ID	Scientific Name
9913	Bos taurus
7957	Carassius auratus
10150	Chinchillidae
8113	Cichlidae
10026	Cricetinae
10029	Cricetulus griseus
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9103	Meleagris gallopavo
10090	Mus musculus
8022	Oncorhynchus mykiss
9986	Oryctolagus cuniculus
9557	Papio hamadryas
10114	Rattus
9376	Soricidae
9823	Sus scrofa
9739	Tursiops truncatus

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Crosslinks: 2

Consortium for Functional Glycomics (CFG):

carbGlipid_20577_D000

GlycoEpitope DB:

EP0056

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Glycosciences.DB structure entry #436: Glycosphingolipid GD1a

1 - 4 of 4 entries with matching glycan part

1 - 5 of 374 literature references

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