Glycosciences.de - Glycosciences.DB entry 19992

☰
- Add title
- Add keywords
- Add publication
- Leave comment

Glycosciences.DB structure entry #19992: Blood group A Type 6 Glycan

■ Expand all ■ Collapse all

Format: CarbBank LINUCS GlycoCT_condensed GlycoCT_xml


 a-D-GalpNAc-(1-3)+
                  |
             b-D-Galp-(1-4)-b-D-Glcp
                  |
    a-L-Fucp-(1-2)+


RES
1b:b-dglc-HEX-1:5
2b:b-dgal-HEX-1:5
3b:a-lgal-HEX-1:5|6:d
4b:a-dgal-HEX-1:5
5s:n-acetyl
LIN
1:1o(4+1)2d
2:2o(2+1)3d
3:2o(3+1)4d
4:4d(2+1)5n


<?xml version="1.0" encoding="UTF-8"?>
 <sugar version="1.0">
 <residues>
 <basetype id="1" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dglc-HEX-1:5">
 <stemtype id="1" type="dglc" />
 </basetype>
 <basetype id="2" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dgal-HEX-1:5">
 <stemtype id="1" type="dgal" />
 </basetype>
 <basetype id="3" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-lgal-HEX-1:5|6:d">
 <stemtype id="1" type="lgal" />
 <modification type="d" pos_one="6" />
 </basetype>
 <basetype id="4" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-dgal-HEX-1:5">
 <stemtype id="1" type="dgal" />
 </basetype>
 <substituent id="5" name="n-acetyl" />
 </residues>
 <linkages>
 <connection id="1" parent="1" child="2">
 <linkage id="1" parentType="o" childType="d">
 <parent pos="4" />
 <child pos="1" />
 </linkage>
 </connection>
 <connection id="2" parent="2" child="3">
 <linkage id="2" parentType="o" childType="d">
 <parent pos="2" />
 <child pos="1" />
 </linkage>
 </connection>
 <connection id="3" parent="2" child="4">
 <linkage id="3" parentType="o" childType="d">
 <parent pos="3" />
 <child pos="1" />
 </linkage>
 </connection>
 <connection id="4" parent="4" child="5">
 <linkage id="4" parentType="d" childType="n">
 <parent pos="2" />
 <child pos="1" />
 </linkage>
 </connection>
 </linkages>
 </sugar>

SNFG-style Graphics

3D Structure Model

download coordinates

Corresponding entries: 3

1 - 3 of 3 entries with matching glycan part

Structure entry #5008:

a-D-GalpNAc-(1-3)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide | a-L-Fucp-(1-2)+

no 3d model

no NMR spectra

literature references

no GlycoMaps

Structure entry #9033:

a-D-GalpNAc-(1-3)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-9)-9-hydroxy-Nonanoate-(1-1)-Methyl | a-L-Fucp-(1-2)+

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #17662:

a-D-GalpNAc-(1-3)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2-propenamide | a-L-Fucp-(1-2)+

no NMR spectra

literature references

no GlycoMaps

Taxons

Blood Group A Antigen (Show) (Search Database)

Blood group A Type 6
BGA type 6

General Structure Data

Chemical Formula:	C₂₆H₄₅N₁O₂₀		#C	#H	#O	#N
Molec. Weight:	691		26	45	20	1
# Atoms:	92
# Residues:	4
# Heavy Atoms:	47

Superclasses:

Hex
Hex	2
dHex	1
HexNAc	1

Residues:

Residue	Count
A-D-GALPNAC	1
A-L-FUCP	1
B-D-GALP	1
B-D-GLCP	1

PDB references: 2

1 - 2 of 2 PDB entries

PDB ID 2j1u: STRUCTURE OF A STREPTOCOCCUS PNEUMONIAE FUCOSE BINDING MODULE IN COMPLEX WITH THE BLOOD GROUP A-TETRASACCHARIDE

Description: FUCOLECTIN-RELATED PROTEIN

Source: STREPTOCOCCUS PNEUMONIAE

Experimental method: X-RAY DIFFRACTION

Resolution: 1.8Å

Release date: 2006-09-06

Entry features 1 distinct glycan structures [1 instances].

PDB ID 1ulf: CGL2 in complex with Blood Group A tetrasaccharide

Description: galectin-2

Source: Coprinopsis cinerea

Experimental method: X-RAY DIFFRACTION

Resolution: 2.36Å

Release date: 2004-04-20

Entry features 1 distinct glycan structures [2 instances].

Conformational maps: 3

Map ID: 8447

Disaccharide Fragment: a-L-Fucp-(1-2)-b-D-Galp

Linkage Path: 42

Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns

Map ID: 8448

Disaccharide Fragment: b-D-Galp-(1-4)-b-D-Glcp

Linkage Path: 4

Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns

Map ID: 8449

Disaccharide Fragment: a-D-GalpNAc-(1-3)-b-D-Galp

Linkage Path: 43

Method: MD MM3(1996) Tinker 4 HTMD, 1000K, 30ns

Literature references: 5

1 - 5 of 5 literature references

Reference #21992

Blenda AV; Kamili NA; Wu SC; Abel WF; Ayona D; Gerner-Smidt C; Ho AD; Benian GM; Cummings RD; Arthur CM; Stowell SR

Galectin-9 recognizes and exhibits antimicrobial activity toward microbes expressing blood group-like antigens.

Published 2022 in J Biol Chem, 298: 101704

Reference contains 42 structures

Reference #22000

Sojitra M; Sarkar S; Maghera J; Rodrigues E; Carpenter EJ; Seth S; Ferrer Vinals D; Bennett NJ; Reddy R; Khalil A; Xue X; Bell MR; Zheng RB; Zhang P; Nycholat C; Bailey JJ; Ling CC; Lowary TL; Paulson JC; Macauley MS; Derda R

Genetically encoded multivalent liquid glycan array displayed on M13 bacteriophage.

Published 2021 in Nat Chem Biol, 17: 806-816

Reference contains 65 structures

Reference #20943

Gildersleeve JC; Wright WS

Diverse molecular recognition properties of blood group A binding monoclonal antibodies.

Published 2016 in Glycobiology, 26: 443-8

Reference contains 14 structures

Reference #21004

Han L; Kitova EN; Tan M; Jiang X; Pluvinage B; Boraston AB; Klassen JS

Affinities of human histo-blood group antigens for norovirus capsid protein complexes.

Published 2015 in Glycobiology, 25: 170-80

Reference contains 14 structures

Reference #12788

Norberg T; Kallin E

Preparation of carbohydrate acrylate and methacrylate copolymers

Published 1990 in PCT Int Appl, 0: 1-24

Reference contains 18 structures

Further literature references from PDB entries: 2

1 - 2 of 2 literature references from PDB entries

Reference #16714

Boraston AB; Wang D; Burke RD

Blood group antigen recognition by a Streptococcus pneumoniae virulence factor.

Published 2006 in J. Biol. Chem., 281: 35263-71

Reference #16429

Walser PJ; Haebel PW; Künzler M; Sargent D; Kües U; Aebi M; Ban N

Structure and functional analysis of the fungal galectin CGL2.

Published 2004 in Structure, 12: 689-702

Consortium for Functional Glycomics (CFG):

■ Expand all ■ Collapse all

© 2010-2016,2022 Justus-Liebig University Giessen, Institute of Veterinary Physiology and Biochemistry, Frankfurter Str. 100, 35392 Giessen, Germany
© 2017-2021 The Glycosciences.de crew
© 1997-2009 German Cancer Research Center Heidelberg, Central Spectroscopic Division, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
All rights reserved.