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Glycosciences.DB structure entry #18364:
a-L-Fucp-(1-2)-b-D-Galp-(1-4)+
|
a-D-GlcpNAc
|
a-L-Fucp-(1-3)+
[][A-D-GLCPNAC]{[(3+1)][A-L-FUCP]{}[(4+1)][B-D-GALP]{[(2+1)][A-L-FUCP]{}}}
RES
1b:a-dglc-HEX-1:5
2s:n-acetyl
3b:a-lgal-HEX-1:5|6:d
4b:b-dgal-HEX-1:5
5b:a-lgal-HEX-1:5|6:d
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:1o(4+1)4d
4:4o(2+1)5d
<?xml version="1.0" encoding="UTF-8"?>
<sugar version="1.0">
<residues>
<basetype id="1" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-dglc-HEX-1:5">
<stemtype id="1" type="dglc" />
</basetype>
<substituent id="2" name="n-acetyl" />
<basetype id="3" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-lgal-HEX-1:5|6:d">
<stemtype id="1" type="lgal" />
<modification type="d" pos_one="6" />
</basetype>
<basetype id="4" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
<basetype id="5" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-lgal-HEX-1:5|6:d">
<stemtype id="1" type="lgal" />
<modification type="d" pos_one="6" />
</basetype>
</residues>
<linkages>
<connection id="1" parent="1" child="2">
<linkage id="1" parentType="d" childType="n">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="2" parent="1" child="3">
<linkage id="2" parentType="o" childType="d">
<parent pos="3" />
<child pos="1" />
</linkage>
</connection>
<connection id="3" parent="1" child="4">
<linkage id="3" parentType="o" childType="d">
<parent pos="4" />
<child pos="1" />
</linkage>
</connection>
<connection id="4" parent="4" child="5">
<linkage id="4" parentType="o" childType="d">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
</linkages>
</sugar>
3D Structure Model- Blood Group H Antigen (Show) (Search Database)
| Chemical Formula: | C26H45N1O19 | #C | #H | #O | #N | |
| Molec. Weight: | 675 | 26 | 45 | 19 | 1 | |
| # Atoms: | 91 | |||||
| # Residues: | 4 | |||||
| # Heavy Atoms: | 46 | |||||
Superclasses:
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Residues:
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PDB references: 91 - 5 of 9 PDB entries
PDB ID 6orh:
Crystal structure of SpGH29
Description: Glycoside hydrolase
Source: Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.62Å
Release date: 2019-07-10
Entry features 1 distinct glycan structures [2 instances].
PDB ID 5elb:
Cholera toxin classical B-pentamer in complex with Lewis-y
Description: Cholera toxin B
Source: Vibrio cholerae
Experimental method: X-RAY DIFFRACTION
Resolution: 1.08Å
Release date: 2016-03-30
Entry features 3 distinct glycan structures [20 instances].
PDB ID 5elc:
Cholera toxin El Tor B-pentamer in complex with Lewis-y
Description: Cholera enterotoxin subunit B
Source: Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Experimental method: X-RAY DIFFRACTION
Resolution: 1.5Å
Release date: 2016-03-30
Entry features 3 distinct glycan structures [10 instances].
PDB ID 4d4u:
Crystal Structure of Fucose binding lectin from Aspergillus Fumigatus (AFL) in complex with LewisY tetrasaccharide.
Description: FUCOSE-SPECIFIC LECTIN FLEA
Source: ASPERGILLUS FUMIGATUS
Experimental method: X-RAY DIFFRACTION
Resolution: 1.99Å
Release date: 2015-03-11
Entry features 4 distinct glycan structures [10 instances].
PDB ID 4rdl:
Crystal structure of Norovirus Boxer P domain in complex with Lewis y tetrasaccharide
Description: Capsid
Source: Human calicivirus NLV/Boxer/2001/US
Experimental method: X-RAY DIFFRACTION
Resolution: 1.449Å
Release date: 2015-01-14
Entry features 1 distinct glycan structures [2 instances].
Literature references: 21 - 2 of 2 literature references
Reference #10918
Pennington JE; Rastan S; Roelcke D; Feizi T
Saccharide structures of the mouse embryo during the first eight days of development. Inferences from immunocytochemical studies using monoclonal antibodies in conjunction with glycosidases
Published 1985 in J Embryol Exp Morphol, 90: 335-361
Reference contains 2 structures
Reference #11524
Jacquinet JC; Sinay P
Synthesis of blood-group substances. 6. Synthesis of O-.alpha.-L-fucopyranosyl-(1-2)-O-.beta.-D-galactopyranosyl-(1-4)-O-[.alpha.-L-fucopyranosyl-(1-3)]-2-acetamido-2-deoxy-.alpha.-D-glucopyranose, the postulated Lewis d antigenic determinant
Published 1977 in J Org Chem, 42: 720-724
Reference contains 1 structure
1 - 5 of 7 literature references from PDB entries
Reference #19530
Heggelund JE; Burschowsky D; Bjørnestad VA; Hodnik V; Anderluh G; Krengel U
High-Resolution Crystal Structures Elucidate the Molecular Basis of Cholera Blood Group Dependence.
Published 2016 in PLoS Pathog., 12: e1005567
Reference #19144
Houser J; Komarek J; Cioci G; Varrot A; Imberty A; Wimmerova M
Structural insights into Aspergillus fumigatus lectin specificity: AFL binding sites are functionally non-equivalent.
Published 2015 in Acta Crystallogr. D Biol. Crystallogr., 71: 442-53
Reference #19074
Hao N; Chen Y; Xia M; Tan M; Liu W; Guan X; Jiang X; Li X; Rao Z
Crystal structures of GI.8 Boxer virus P dimers in complex with HBGAs, a novel evolutionary path selected by the Lewis epitope.
Published 2015 in Protein Cell, 6: 101-16
Reference #19039
Singh BK; Leuthold MM; Hansman GS
Human noroviruses' fondness for histo-blood group antigens.
Published 2015 in J. Virol., 89: 2024-40
Reference #17926
Chen Y; Tan M; Xia M; Hao N; Zhang XC; Huang P; Jiang X; Li X; Rao Z
Crystallography of a Lewis-binding norovirus, elucidation of strain-specificity to the polymorphic human histo-blood group antigens.
Published 2011 in PLoS Pathog., 7: e1002152
| NCBI Taxonomy ID | Scientific Name |
| 10090 | Mus musculus |
Consortium for Functional Glycomics (CFG):
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