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Glycosciences.DB structure entry #170: Sialyl-Tn antigen (Ser-linked)
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-3)-Ser
[][SER]{[(3+1)][A-D-GALPNAC]{[(6+2)][A-D-NEUP5AC]{}}}
<?xml version="1.0" encoding="UTF-8"?>
<sugar version="1.0">
<residues>
<basetype id="1" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
<substituent id="2" name="n-acetyl" />
<basetype id="3" anomer="a" superclass="non" ringStart="2" ringEnd="6" name="a-dgro-dgal-NON-2:6|1:a|2:keto|3:d">
<stemtype id="1" type="dgro" />
<stemtype id="2" type="dgal" />
<modification type="a" pos_one="1" />
<modification type="keto" pos_one="2" />
<modification type="d" pos_one="3" />
</basetype>
<substituent id="4" name="n-acetyl" />
</residues>
<linkages>
<connection id="1" parent="1" child="2">
<linkage id="1" parentType="d" childType="n">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="2" parent="1" child="3">
<linkage id="2" parentType="o" childType="d">
<parent pos="6" />
<child pos="2" />
</linkage>
</connection>
<connection id="3" parent="3" child="4">
<linkage id="3" parentType="d" childType="n">
<parent pos="5" />
<child pos="1" />
</linkage>
</connection>
</linkages>
<aglyca>
<historicalData>
<entry id="0" name="SER" toResidue="1">
<linkage parentType="n" childType="x">
<parent pos="3" />
<child pos="1" />
</linkage>
</entry>
</historicalData>
</aglyca>
</sugar>
3D Structure Model1 - 5 of 10 entries with matching glycan part
Structure entry #576: SSV peptide with two Sialyl-Tn antigens
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-3)+
|
Ser-(1-2)-Val
|
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-3)-Ser-(1-2)+
 |
 |
 |
 : 1 |
 |
Taxons |
Structure entry #577: SSSV peptide with three Sialyl-Tn antigens
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-3)+
|
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-3)+ Ser-(1-2)-Val
| |
Ser-(1-2)+
|
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-3)-Ser-(1-2)+
|
|
|
: 1 |
|
Taxons |
Structure entry #730:
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-1)-<Crotyl>
|
|
|
: 1 |
|
Taxons |
Structure entry #2330:
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-1)-But-2-en-yl
|
|
|
: 1 |
|
Taxons |
Structure entry #2331:
a-D-Neup5Ac-(2-6)-a-D-GalpNAc-(1-1)-<Crotyl-KLH/HSA>
|
|
|
: 1 |
|
Taxons |
- sialyl Tn antigen
- sialyl-Tn antigen
| Chemical Formula: | C22H37N3O15 | #C | #H | #O | #N | |
| Molec. Weight: | 583 | 22 | 37 | 15 | 3 | |
| # Atoms: | 77 | |||||
| # Residues: | 3 | |||||
| # Heavy Atoms: | 40 | |||||
Superclasses:
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Residues:
|
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Literature references: 791 - 5 of 79 literature references
Reference #21993
Konstantinidi A; Nason R; Čaval T; Sun L; Sørensen DM; Furukawa S; Ye Z; Vincentelli R; Narimatsu Y; Vakhrushev SY; Clausen H
Exploring the glycosylation of mucins by use of O-glycodomain reporters recombinantly expressed in glycoengineered HEK293 cells.
Published 2022 in J Biol Chem, 298: 101784
Reference contains 10 structures
Reference #21766
Rodriguez E; Boelaars K; Brown K; Madunić K; van Ee T; Dijk F; Verheij J; Li RJE; Schetters STT; Meijer LL; Le Large TYS; Driehuis E; Clevers H; Bruijns SCM; O'Toole T; van Vliet SJ; Bijlsma MF; Wuhrer M; Kazemier G; Giovannetti E; Garcia-Vallejo JJ; va
Analysis of the glyco-code in pancreatic ductal adenocarcinoma identifies glycan-mediated immune regulatory circuits.
Published 2022 in Commun Biol, 5: 41
Reference contains 10 structures
Reference #21645
Li C; Palma AS; Zhang P; Zhang Y; Gao C; Silva LM; Li Z; Trovão F; Weishaupt M; Seeberger PH; Likhosherstov LM; Piskarev V; Yu J; Westerlind U; Chai W
Noncovalent microarrays from synthetic amino-terminating glycans: Implications in expanding glycan microarray diversity and platform comparison.
Published 2021 in Glycobiology, 31: 931-946
Reference contains 41 structures
Reference #21716
Sun L; Konstantinidi A; Ye Z; Nason R; Zhang Y; Büll C; Kahl-Knutson B; Hansen L; Leffler H; Vakhrushev SY; Yang Z; Clausen H; Narimatsu Y
Installation of O-glycan sulfation capacities in human HEK293 cells for display of sulfated mucins.
Published 2021 in J Biol Chem, : 101382
Reference contains 12 structures
Reference #21609
Murugesan G; Correia VG; Palma AS; Chai W; Li C; Feizi T; Martin E; Laux B; Franz A; Fuchs K; Weigle B; Crocker PR
Siglec-15 recognition of sialoglycans on tumor cell lines can occur independently of sialyl Tn antigen expression.
Published 2021 in Glycobiology, 31: 44-54
Reference contains 16 structures
| NCBI Taxonomy ID | Scientific Name |
| 96820 | Armadillo |
| 9913 | Bos taurus |
| 9606 | Homo sapiens |
| 12721 | Human immunodeficiency virus |
| 10090 | Mus musculus |
| 9986 | Oryctolagus cuniculus |
| 10114 | Rattus |
Consortium for Functional Glycomics (CFG):
GlycoEpitope DB:
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