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Glycosciences.DB structure entry #169: Glycosphingolipid GT1b


 a-D-Neup5Ac-(2-3)-b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+
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                                              b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide
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                a-D-Neup5Ac-(2-8)-a-D-Neup5Ac-(2-3)+

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Corresponding entries: 2

1 - 2 of 2 entries with matching glycan part

Structure entry #16820:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-O)-<BSA> | a-D-Neup5Ac-(2-8)-a-D-Neup5Ac-(2-3)+

: 1

Taxons

Structure entry #22460:

a-D-neup5ac-(2-3)-b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)-b-D-Galp-(1-4)-b-D-Glcp | a-D-Neup5ac-(2-8)-a-D-Neup5ac-(2-3)+

Taxons

GSL core, ganglio-type (Show) (Search Database)

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Trivial names

GT1b
IV3Neu5AcII3(Neu5Ac)2Gg4Cer

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Keywords

glycosphingolipid

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General Structure Data

Chemical Formula:	C₉₂H₁₅₉N₅O₄₇	#C	#H	#O	#N
Molec. Weight:	2086	92	159	47	5
# Atoms:	303
# Residues:	8
# Heavy Atoms:	144

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Composition

Superclasses:

Neu		Hex
NeuAc	3	Hex	3
		HexNAc	1

Residues:

Residue	Count
A-D-NEUP5AC	3
B-D-GALP	2
B-D-GALPNAC	1
B-D-GLCP	1
CERAMIDE	1

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NMR Carbon Chemical Shift Info

MHz	0
Temperature	0
Solvent	D2O
Residue	Linkage	Carbon	PPM	JFrom	JTo	Hz	Note
b-D-Glcp	4,1	C1	103.50			0
b-D-Glcp	4,1	C2	73.70			0
b-D-Glcp	4,1	C3	75.00			0
b-D-Glcp	4,1	C4	79.40			0
b-D-Glcp	4,1	C5	75.50			0
b-D-Glcp	4,1	C6	60.80			0
b-D-Galp	4,4,1	C1	103.50			0
b-D-Galp	4,4,1	C2	70.40			0
b-D-Galp	4,4,1	C3	75.00			0
b-D-Galp	4,4,1	C4	78.80			0
b-D-Galp	4,4,1	C5	75.00			0
b-D-Galp	4,4,1	C6	61.80			0
b-D-GalpNAc	4,4,4,1	C1	103.50			0
b-D-GalpNAc	4,4,4,1	C2	53.30			0
b-D-GalpNAc	4,4,4,1	C3	81.10			0
b-D-GalpNAc	4,4,4,1	C4	68.50			0
b-D-GalpNAc	4,4,4,1	C5	75.50			0
b-D-GalpNAc	4,4,4,1	C6	61.50			0
b-D-Galp	3,4,4,4,1	C1	105.30			0
b-D-Galp	3,4,4,4,1	C2	70.40			0
b-D-Galp	3,4,4,4,1	C3	76.50			0
b-D-Galp	3,4,4,4,1	C4	69.10			0
b-D-Galp	3,4,4,4,1	C5	75.50			0
b-D-Galp	3,4,4,4,1	C6	61.80			0
a-D-Neup5Ac	3,3,4,4,4,1	C1	174.60			0
a-D-Neup5Ac	3,3,4,4,4,1	C2	100.70			0
a-D-Neup5Ac	3,3,4,4,4,1	C3	40.70			0
a-D-Neup5Ac	3,3,4,4,4,1	C4	69.10			0
a-D-Neup5Ac	3,3,4,4,4,1	C5	52.90			0
a-D-Neup5Ac	3,3,4,4,4,1	C6	73.70			0
a-D-Neup5Ac	3,3,4,4,4,1	C7	69.10			0
a-D-Neup5Ac	3,3,4,4,4,1	C8	72.50			0
a-D-Neup5Ac	3,3,4,4,4,1	C9	63.50			0
a-D-Neup5Ac	3,4,4,1	C1	174.10			0
a-D-Neup5Ac	3,4,4,1	C2	101.50			0
a-D-Neup5Ac	3,4,4,1	C3	40.00			0
a-D-Neup5Ac	3,4,4,1	C4	69.10			0
a-D-Neup5Ac	3,4,4,1	C5	52.20			0
a-D-Neup5Ac	3,4,4,1	C6	73.70			0
a-D-Neup5Ac	3,4,4,1	C7	69.10			0
a-D-Neup5Ac	3,4,4,1	C8	77.10			0
a-D-Neup5Ac	3,4,4,1	C9	62.50			0
a-D-Neup5Ac	8,3,4,4,1	C1	174.10			0
a-D-Neup5Ac	8,3,4,4,1	C2	101.50			0
a-D-Neup5Ac	8,3,4,4,1	C3	41.60			0
a-D-Neup5Ac	8,3,4,4,1	C4	69.10			0
a-D-Neup5Ac	8,3,4,4,1	C5	52.90			0
a-D-Neup5Ac	8,3,4,4,1	C6	73.70			0
a-D-Neup5Ac	8,3,4,4,1	C7	69.10			0
a-D-Neup5Ac	8,3,4,4,1	C8	72.50			0
a-D-Neup5Ac	8,3,4,4,1	C9	63.50			0

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Literature references: 290

1 - 5 of 290 literature references

Reference #21691

Nguyen L; McCord KA; Bui DT; Bouwman KM; Kitova EN; Elaish M; Kumawat D; Daskhan GC; Tomris I; Han L; Chopra P; Yang TJ; Willows SD; Mason AL; Mahal LK; Lowary TL; West LJ; Hsu SD; Hobman T; Tompkins SM; Boons GJ; de Vries RP; Macauley MS; Klassen JS

Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.

Published 2022 in Nat Chem Biol, 18: 81-90

Reference contains 33 structures

Reference #21970

He X; Guan F; Lei L

Structure and function of glycosphingolipids on small extracellular vesicles.

Published 2022 in Glycoconj J, 39: 197-205

Reference contains 8 structures

Reference #21955

Zalem D; Juhás M; Terrinoni M; King-Lyons N; Lebens M; Varrot A; Connell TD; Teneberg S

Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.

Published 2022 in Glycobiology, 32: 391-403

Reference contains 29 structures

Reference #21976

Araki E; Hane M; Hatanaka R; Kimura R; Tsuda K; Konishi M; Komura N; Ando H; Kitajima K; Sato C

Analysis of biochemical features of ST8 α-N-acetyl-neuraminide α2,8-sialyltransferase (St8sia) 5 isoforms.

Published 2022 in Glycoconj J, 39: 291-302

Reference contains 7 structures

Reference #21969

Liang YJ

Glycosphingolipids in human embryonic stem cells and breast cancer stem cells, and potential cancer therapy strategies based on their structures and functions.

Published 2022 in Glycoconj J, 39: 177-195

Reference contains 21 structures

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Taxonomy: 16

NCBI Taxonomy ID	Scientific Name
9913	Bos taurus
7957	Carassius auratus
10150	Chinchillidae
10026	Cricetinae
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9103	Meleagris gallopavo
10090	Mus musculus
9986	Oryctolagus cuniculus
9557	Papio hamadryas
30475	Rajidae
10114	Rattus
9376	Soricidae
9823	Sus scrofa
9739	Tursiops truncatus

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Crosslinks: 2

Consortium for Functional Glycomics (CFG):

carbGlipid_21097_D000

GlycoEpitope DB:

EP0067

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Glycosciences.DB structure entry #169: Glycosphingolipid GT1b

1 - 2 of 2 entries with matching glycan part

1 - 5 of 290 literature references

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