Glycosciences.de - Glycosciences.DB entry 168

☰
- Add title
- Add keywords
- Add publication
- Leave comment

Glycosciences.DB structure entry #168: Glycosphingolipid GM3

■ Expand all ■ Collapse all

Format: CarbBank LINUCS


 a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide

Corresponding entries: 15

1 - 5 of 15 entries with matching glycan part

Structure entry #520:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Methyl

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #761: Lyso-GM3

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Sphingosine

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #2180:

a-D-Neup5Ac-(2-3/6)-b-D-Galp-(1-4)-b-D-Glcp

no NMR spectra

literature references

no GlycoMaps

Structure entry #3247:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-<tetradecylhexadecyl>

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #3943:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol

no NMR spectra

literature references

no GlycoMaps

GM3 (Show) (Search Database)

GM3
GM3-Cer
II3Neu5AcLacCer

glycosphingolipid

General Structure Data

Chemical Formula:	C₅₆H₁₀₂N₂O₂₁		#C	#H	#O	#N
Molec. Weight:	1139		56	102	21	2
# Atoms:	181
# Residues:	4
# Heavy Atoms:	79

Superclasses:

Neu		Hex
NeuAc	1	Hex	2

Residues:

Residue	Count
A-D-NEUP5AC	1
B-D-GALP	1
B-D-GLCP	1
CERAMIDE	1

NMR Carbon Chemical Shift Info

MHz	0
Temperature	0
Solvent	D2O
Residue	Linkage	Carbon	PPM	JFrom	JTo	Hz	Note
b-D-Glcp	4,1	C1	103.60			0
b-D-Glcp	4,1	C2	74.00			0
b-D-Glcp	4,1	C3	75.40			0
b-D-Glcp	4,1	C4	80.00			0
b-D-Glcp	4,1	C5	75.80			0
b-D-Glcp	4,1	C6	61.30			0
b-D-Galp	4,4,1	C1	103.90			0
b-D-Galp	4,4,1	C2	70.40			0
b-D-Galp	4,4,1	C3	76.60			0
b-D-Galp	4,4,1	C4	68.60			0
b-D-Galp	4,4,1	C5	76.10			0
b-D-Galp	4,4,1	C6	62.00			0
a-D-Neup5Ac	3,4,4,1	C1	174.60			0
a-D-Neup5Ac	3,4,4,1	C2	100.90			0
a-D-Neup5Ac	3,4,4,1	C3	40.80			0
a-D-Neup5Ac	3,4,4,1	C4	69.20			0
a-D-Neup5Ac	3,4,4,1	C5	53.00			0
a-D-Neup5Ac	3,4,4,1	C6	74.00			0
a-D-Neup5Ac	3,4,4,1	C7	69.40			0
a-D-Neup5Ac	3,4,4,1	C8	72.70			0
a-D-Neup5Ac	3,4,4,1	C9	63.80			0

PDB references: 1

1 - 1 of 1 PDB entries

PDB ID 5j14: Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3

Description: Putative secreted endoglycosylceramidase

Source: Rhodococcus equi 103S

Experimental method: X-RAY DIFFRACTION

Resolution: 1.915Å

Release date: 2016-04-27

Entry features 2 distinct glycan structures [2 instances].

Literature references: 498

1 - 5 of 498 literature references

Reference #21970

He X; Guan F; Lei L

Structure and function of glycosphingolipids on small extracellular vesicles.

Published 2022 in Glycoconj J, 39: 197-205

Reference contains 8 structures

Reference #21955

Zalem D; Juhás M; Terrinoni M; King-Lyons N; Lebens M; Varrot A; Connell TD; Teneberg S

Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.

Published 2022 in Glycobiology, 32: 391-403

Reference contains 29 structures

Reference #21968

Furukawa K; Ohmi Y; Hamamura K; Kondo Y; Ohkawa Y; Kaneko K; Hashimoto N; Yesmin F; Bhuiyan RH; Tajima O; Furukawa K

Signaling domains of cancer-associated glycolipids.

Published 2022 in Glycoconj J, 39: 145-155

Reference contains 11 structures

Reference #21973

Inokuchi JI; Nagafuku M

Gangliosides in T cell development and function of mice.

Published 2022 in Glycoconj J, 39: 229-238

Reference contains 9 structures

Reference #21691

Nguyen L; McCord KA; Bui DT; Bouwman KM; Kitova EN; Elaish M; Kumawat D; Daskhan GC; Tomris I; Han L; Chopra P; Yang TJ; Willows SD; Mason AL; Mahal LK; Lowary TL; West LJ; Hsu SD; Hobman T; Tompkins SM; Boons GJ; de Vries RP; Macauley MS; Klassen JS

Sialic acid-containing glycolipids mediate binding and viral entry of SARS-CoV-2.

Published 2022 in Nat Chem Biol, 18: 81-90

Reference contains 33 structures

NCBI Taxonomy ID	Scientific Name
9913	Bos taurus
9615	Canis familiaris
7957	Carassius auratus
10141	Cavia porcellus
10150	Chinchillidae
10026	Cricetinae
10029	Cricetulus griseus
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9544	Macaca mulatta
10090	Mus musculus
8022	Oncorhynchus mykiss
9986	Oryctolagus cuniculus
9940	Ovis aries
9557	Papio hamadryas
10114	Rattus
9823	Sus scrofa

GlycoEpitope DB:

EP0053

■ Expand all ■ Collapse all

© 2010-2016,2022 Justus-Liebig University Giessen, Institute of Veterinary Physiology and Biochemistry, Frankfurter Str. 100, 35392 Giessen, Germany
© 2017-2021 The Glycosciences.de crew
© 1997-2009 German Cancer Research Center Heidelberg, Central Spectroscopic Division, Im Neuenheimer Feld 280, 69120 Heidelberg, Germany
All rights reserved.