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Glycosciences.DB structure entry #168: Glycosphingolipid GM3

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Format: CarbBank LINUCS


 a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide

Corresponding entries: 15

1 - 5 of 15 entries with matching glycan part

Structure entry #520:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Methyl

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #761: Lyso-GM3

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Sphingosine

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #2180:

a-D-Neup5Ac-(2-3/6)-b-D-Galp-(1-4)-b-D-Glcp

no NMR spectra

literature references

no GlycoMaps

Structure entry #3247:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-<tetradecylhexadecyl>

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #3943:

a-D-Neup5Ac-(2-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol

no NMR spectra

literature references

no GlycoMaps

GM3 (Show) (Search Database)

GM3
GM3-Cer
II3Neu5AcLacCer

glycosphingolipid

General Structure Data

Chemical Formula:	C₅₆H₁₀₂N₂O₂₁		#C	#H	#O	#N
Molec. Weight:	1139		56	102	21	2
# Atoms:	181
# Residues:	4
# Heavy Atoms:	79

Superclasses:

Neu		Hex
NeuAc	1	Hex	2

Residues:

Residue	Count
A-D-NEUP5AC	1
B-D-GALP	1
B-D-GLCP	1
CERAMIDE	1

NMR Carbon Chemical Shift Info

MHz	0
Temperature	0
Solvent	D2O
Residue	Linkage	Carbon	PPM	JFrom	JTo	Hz	Note
b-D-Glcp	4,1	C1	103.60			0
b-D-Glcp	4,1	C2	74.00			0
b-D-Glcp	4,1	C3	75.40			0
b-D-Glcp	4,1	C4	80.00			0
b-D-Glcp	4,1	C5	75.80			0
b-D-Glcp	4,1	C6	61.30			0
b-D-Galp	4,4,1	C1	103.90			0
b-D-Galp	4,4,1	C2	70.40			0
b-D-Galp	4,4,1	C3	76.60			0
b-D-Galp	4,4,1	C4	68.60			0
b-D-Galp	4,4,1	C5	76.10			0
b-D-Galp	4,4,1	C6	62.00			0
a-D-Neup5Ac	3,4,4,1	C1	174.60			0
a-D-Neup5Ac	3,4,4,1	C2	100.90			0
a-D-Neup5Ac	3,4,4,1	C3	40.80			0
a-D-Neup5Ac	3,4,4,1	C4	69.20			0
a-D-Neup5Ac	3,4,4,1	C5	53.00			0
a-D-Neup5Ac	3,4,4,1	C6	74.00			0
a-D-Neup5Ac	3,4,4,1	C7	69.40			0
a-D-Neup5Ac	3,4,4,1	C8	72.70			0
a-D-Neup5Ac	3,4,4,1	C9	63.80			0

PDB references: 1

1 - 1 of 1 PDB entries

PDB ID 5j14: Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3

Description: Putative secreted endoglycosylceramidase

Source: Rhodococcus equi 103S

Experimental method: X-RAY DIFFRACTION

Resolution: 1.915Å

Release date: 2016-04-27

Entry features 2 distinct glycan structures [2 instances].

Literature references: 501

1 - 5 of 501 literature references

Reference #21969

Glycosphingolipids in human embryonic stem cells and breast cancer stem cells, and potential cancer therapy strategies based on their structures and functions.

Published 2022 in Glycoconj J, 39: 177-195

Reference contains 21 structures

Reference #21976

Araki E; Hane M; Hatanaka R; Kimura R; Tsuda K; Konishi M; Komura N; Ando H; Kitajima K; Sato C

Analysis of biochemical features of ST8 α-N-acetyl-neuraminide α2,8-sialyltransferase (St8sia) 5 isoforms.

Published 2022 in Glycoconj J, 39: 291-302

Reference contains 7 structures

Reference #22500

Kawashima N; Naito S; Hanamatsu H; Nagane M; Takeuchi Y; Furukawa JI; Iwasaki N; Yamashita T; Nakayama KI

Glycosphingolipid GM3 prevents albuminuria and podocytopathy induced by anti-nephrin antibody.

Published 2022 in Sci Rep, 12: 16058

Reference contains 1 structure

Reference #21964

Brockhausen I; Schutzbach J; Wang J; Fishwick B; Brockhausen J

Glycoconjugate journal special issue on: the glycobiology of Parkinson's disease.

Published 2022 in Glycoconj J, 39: 55-74

Reference contains 9 structures

Reference #21970

He X; Guan F; Lei L

Structure and function of glycosphingolipids on small extracellular vesicles.

Published 2022 in Glycoconj J, 39: 197-205

Reference contains 8 structures

NCBI Taxonomy ID	Scientific Name
9913	Bos taurus
9615	Canis familiaris
7957	Carassius auratus
10141	Cavia porcellus
10150	Chinchillidae
10026	Cricetinae
10029	Cricetulus griseus
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9544	Macaca mulatta
10090	Mus musculus
8022	Oncorhynchus mykiss
9986	Oryctolagus cuniculus
9940	Ovis aries
9557	Papio hamadryas
10114	Rattus
9823	Sus scrofa

GlycoEpitope DB:

EP0053

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