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Glycosciences.DB structure entry #146: Lactotetraosylceramide / Lc4

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Format: CarbBank LINUCS


 b-D-Galp-(1-3)-b-D-GlcpNAc-(1-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide

Corresponding entries: 4

1 - 4 of 4 entries with matching glycan part

Structure entry #8306:

b-D-Galp-(1-3)-b-D-GlcpNAc-(1-3)-b-D-Galp-(1-4)-b-D-Glcp

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #9061:

b-D-Galp-(1-3)-b-D-GlcpNAc-(1-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-<4-nitrophenol>

no 3d model

NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #17665:

b-D-Galp-(1-3)-b-D-GlcpNAc-(1-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2-propenamide

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #19870:

b-D-Galp-(1-3)-b-D-GlcpNAc-(1-3)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-<acylamide>

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

GSL core, lacto-type (Show) (Search Database)
Lewis C (Show) (Search Database)

Lactotetraosylceramide
Lc4
Lactotetra

glycosphingolipid

General Structure Data

Chemical Formula:	C₅₉H₁₀₈N₂O₂₃		#C	#H	#O	#N
Molec. Weight:	1213		59	108	23	2
# Atoms:	192
# Residues:	5
# Heavy Atoms:	84

Superclasses:

Hex
Hex	3
HexNAc	1

Residues:

Residue	Count
B-D-GALP	2
B-D-GLCP	1
B-D-GLCPNAC	1
CERAMIDE	1

Literature references: 50

1 - 5 of 50 literature references

Reference #21969

Glycosphingolipids in human embryonic stem cells and breast cancer stem cells, and potential cancer therapy strategies based on their structures and functions.

Published 2022 in Glycoconj J, 39: 177-195

Reference contains 21 structures

Reference #21991

Jin C; Teneberg S

Characterization of novel nonacid glycosphingolipids as biomarkers of human gastric adenocarcinoma.

Published 2022 in J Biol Chem, 298: 101732

Reference contains 18 structures

Reference #21615

Petit D; Teppa RE; Harduin-Lepers A

A phylogenetic view and functional annotation of the animal β1,3-glycosyltransferases of the GT31 CAZy family.

Published 2021 in Glycobiology, 31: 243-259

Reference contains 22 structures

Reference #21331

Indellicato R; Domenighini R; Malagolini N; Cereda A; Mamoli D; Pezzani L; Iascone M; dall'Olio F; Trinchera M

A novel nonsense and inactivating variant of ST3GAL3 in two infant siblings suffering severe epilepsy and expressing circulating CA19.9.

Published 2020 in Glycobiology, 30: 95-104

Reference contains 6 structures

Reference #20516

Säljö K; Barone A; Vizlin-Hodzic D; Johansson BR; Breimer ME; Funa K; Teneberg S

Comparison of the glycosphingolipids of human-induced pluripotent stem cells and human embryonic stem cells.

Published 2017 in Glycobiology, 27: 291-305

Reference contains 27 structures

NCBI Taxonomy ID	Scientific Name
9606	Homo sapiens
9940	Ovis aries
9823	Sus scrofa

Consortium for Functional Glycomics (CFG):

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