Glycosciences.de - Glycosciences.DB entry 142

☰
- Add title
- Add keywords
- Add publication
- Leave comment

Glycosciences.DB structure entry #142: Glycosphingolipid GM1 / GM1a


 b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+
                                 |
                            b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide
                                 |
                a-D-Neup5Ac-(2-3)+

▴

▶

Corresponding entries: 22

1 - 5 of 22 entries with matching glycan part

Structure entry #765:

b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-<2-D-erythro-2-acetamide-octadec-4E-en-1,3-diol> | a-D-Neup5Ac-(2-3)+

: 2

Taxons

Structure entry #766:

b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-sphingosine-(2-1)-<2-chloroacetate> | a-D-Neup5Ac-(2-3)+

: 5

Taxons

Structure entry #2677:

b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp | a-D-Neup5Ac-(2-3)+

: 15

: 101

Taxons

Structure entry #2875:

b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-hexyl | a-D-Neup5Ac-(2-3)+

: 1

Taxons

Structure entry #3946:

b-D-Galp-(1-3)-b-D-GalpNAc-(1-4)+ | b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol | a-D-Neup5Ac-(2-3)+

GSL core, ganglio-type (Show) (Search Database)
GM1a (Show) (Search Database)

▴

▶

Trivial names

GM1
GM1a
II3Neu5AcGg4Cer

▴

▶

Keywords

glycosphingolipid

▴

▶

General Structure Data

Chemical Formula:	C₇₀H₁₂₅N₃O₃₁	#C	#H	#O	#N
Molec. Weight:	1504	70	125	31	3
# Atoms:	229
# Residues:	6
# Heavy Atoms:	104

▴

▶

Composition

Superclasses:

Neu		Hex
NeuAc	1	Hex	3
		HexNAc	1

Residues:

Residue	Count
A-D-NEUP5AC	1
B-D-GALP	2
B-D-GALPNAC	1
B-D-GLCP	1
CERAMIDE	1

▴

▶

NMR Carbon Chemical Shift Info

MHz	0
Temperature	0
Solvent	D2O
Residue	Linkage	Carbon	PPM	JFrom	JTo	Hz	Note
b-D-Glcp	1,4,1	C1	103.40			0
b-D-Glcp	1,4,1	C2	74.10			0
b-D-Glcp	1,4,1	C3	75.20			0
b-D-Glcp	1,4,1	C4	79.80			0
b-D-Glcp	1,4,1	C5	75.70			0
b-D-Glcp	1,4,1	C6	61.00			0
b-D-Galp	4,1,4,1	C1	103.40			0
b-D-Galp	4,1,4,1	C2	70.70			0
b-D-Galp	4,1,4,1	C3	75.20			0
b-D-Galp	4,1,4,1	C4	78.10			0
b-D-Galp	4,1,4,1	C5	75.00			0
b-D-Galp	4,1,4,1	C6	61.80			0
b-D-GalpNAc	4,4,1,4,1	C1	103.40			0
b-D-GalpNAc	4,4,1,4,1	C2	52.80			0
b-D-GalpNAc	4,4,1,4,1	C3	81.50			0
b-D-GalpNAc	4,4,1,4,1	C4	68.80			0
b-D-GalpNAc	4,4,1,4,1	C5	75.70			0
b-D-GalpNAc	4,4,1,4,1	C6	61.40			0
b-D-Galp	3,4,4,1,4,1	C1	105.60			0
b-D-Galp	3,4,4,1,4,1	C2	71.70			0
b-D-Galp	3,4,4,1,4,1	C3	73.60			0
b-D-Galp	3,4,4,1,4,1	C4	69.20			0
b-D-Galp	3,4,4,1,4,1	C5	75.70			0
b-D-Galp	3,4,4,1,4,1	C6	61.40			0
a-D-Neup5Ac	3,4,1,4,1	C1	174.50			0
a-D-Neup5Ac	3,4,1,4,1	C2	102.50			0
a-D-Neup5Ac	3,4,1,4,1	C3	37.80			0
a-D-Neup5Ac	3,4,1,4,1	C4	69.20			0
a-D-Neup5Ac	3,4,1,4,1	C5	52.00			0
a-D-Neup5Ac	3,4,1,4,1	C6	73.60			0
a-D-Neup5Ac	3,4,1,4,1	C7	69.20			0
a-D-Neup5Ac	3,4,1,4,1	C8	72.90			0
a-D-Neup5Ac	3,4,1,4,1	C9	64.00			0

▴

▶

PDB references: 1

1 - 1 of 1 PDB entries

PDB ID 5j7z: Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM1

Description: Putative secreted endoglycosylceramidase

Source: Rhodococcus equi 103S

Experimental method: X-RAY DIFFRACTION

Resolution: 2.15Å

Release date: 2016-04-27

Entry features 1 distinct glycan structures [1 instances].

▴

▼

Literature references: 659

1 - 5 of 659 literature references

Reference #21964

Brockhausen I; Schutzbach J; Wang J; Fishwick B; Brockhausen J

Glycoconjugate journal special issue on: the glycobiology of Parkinson's disease.

Published 2022 in Glycoconj J, 39: 55-74

Reference contains 9 structures

Reference #21968

Furukawa K; Ohmi Y; Hamamura K; Kondo Y; Ohkawa Y; Kaneko K; Hashimoto N; Yesmin F; Bhuiyan RH; Tajima O; Furukawa K

Signaling domains of cancer-associated glycolipids.

Published 2022 in Glycoconj J, 39: 145-155

Reference contains 11 structures

Reference #21973

Inokuchi JI; Nagafuku M

Gangliosides in T cell development and function of mice.

Published 2022 in Glycoconj J, 39: 229-238

Reference contains 9 structures

Reference #21692

Uraki R; Kawaoka Y

Host glycolipids in SARS-CoV-2 entry.

Published 2022 in Nat Chem Biol, 18: 6-7

Reference contains 2 structures

Reference #21955

Zalem D; Juhás M; Terrinoni M; King-Lyons N; Lebens M; Varrot A; Connell TD; Teneberg S

Characterization of the ganglioside recognition profile of Escherichia coli heat-labile enterotoxin LT-IIc.

Published 2022 in Glycobiology, 32: 391-403

Reference contains 29 structures

▴

▶

Taxonomy: 20

NCBI Taxonomy ID	Scientific Name
9913	Bos taurus
7957	Carassius auratus
10141	Cavia porcellus
10150	Chinchillidae
8113	Cichlidae
10026	Cricetinae
10029	Cricetulus griseus
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9542	Macaca fuscata
9544	Macaca mulatta
10090	Mus musculus
9986	Oryctolagus cuniculus
9940	Ovis aries
9557	Papio hamadryas
10114	Rattus
9376	Soricidae
9823	Sus scrofa
9739	Tursiops truncatus

▴

▶

Crosslinks: 2

Consortium for Functional Glycomics (CFG):

carbGlipid_21020_D000

GlycoEpitope DB:

EP0050

■ Expand all ■ Collapse all

Glycosciences.DB structure entry #142: Glycosphingolipid GM1 / GM1a

1 - 5 of 22 entries with matching glycan part

1 - 1 of 1 PDB entries

1 - 5 of 659 literature references

Add title to glycan structure entry:

Add keyword to glycan structure entry:

Add publication to glycan structure entry:

Leave a comment on this glycan structure entry: