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Glycosciences.DB structure entry #138: Glycosphingolipid Gb3 / CTH / Pk antigen

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Format: CarbBank LINUCS


 a-D-Galp-(1-4)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide

Corresponding entries: 10

1 - 5 of 10 entries with matching glycan part

Structure entry #342:

a-D-Galp-(1-4)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Methyl

no 3d model

NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #3457:

a-D-Galp-(1-4)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #7425:

a-D-Galp-(1-4)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ethyl

no 3d model

no NMR spectra

literature references

no GlycoMaps

Structure entry #7626:

a-D-Galp-(1-4)-b-D-Galp-(1-4)-b-D-Glcp

no NMR spectra

literature references

GlycoMaps

Taxons

Structure entry #8422: globotriaosylsphingosine (lysoGb3)

a-D-Galp-(1-4)-b-D-Galp-(1-4)-b-D-Glcp-(1-1)-sphingosine

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Pk Antigen (Show) (Search Database)

Globotriaosylceramide
Pk antigen
Gb3
Gb3Cer

glycosphingolipid

General Structure Data

Chemical Formula:	C₅₁H₉₅N₁O₁₈		#C	#H	#O	#N
Molec. Weight:	1010		51	95	18	1
# Atoms:	165
# Residues:	4
# Heavy Atoms:	70

Superclasses:

Hex
Hex	3

Residues:

Residue	Count
A-D-GALP	1
B-D-GALP	1
B-D-GLCP	1
CERAMIDE	1

Literature references: 206

1 - 5 of 206 literature references

Reference #21881

Cecioni S; Ashmus RA; Gilormini PA; Zhu S; Chen X; Shan X; Gros C; Deen MC; Wang Y; Britton R; Vocadlo DJ

Quantifying lysosomal glycosidase activity within cells using bis-acetal substrates.

Published 2022 in Nat Chem Biol, : Online ahead of print

Reference contains 5 structures

Reference #21991

Jin C; Teneberg S

Characterization of novel nonacid glycosphingolipids as biomarkers of human gastric adenocarcinoma.

Published 2022 in J Biol Chem, 298: 101732

Reference contains 18 structures

Reference #21968

Furukawa K; Ohmi Y; Hamamura K; Kondo Y; Ohkawa Y; Kaneko K; Hashimoto N; Yesmin F; Bhuiyan RH; Tajima O; Furukawa K

Signaling domains of cancer-associated glycolipids.

Published 2022 in Glycoconj J, 39: 145-155

Reference contains 11 structures

Reference #22480

Notova S; Bonnardel F; Rosato F; Siukstaite L; Schwaiger J; Lim JH; Bovin N; Varrot A; Ogawa Y; Römer W; Lisacek F; Imberty A

The choanoflagellate pore-forming lectin SaroL-1 punches holes in cancer cells by targeting the tumor-related glycosphingolipid Gb3.

Published 2022 in Commun Biol, 5: 954

Reference contains 7 structures

Reference #21970

He X; Guan F; Lei L

Structure and function of glycosphingolipids on small extracellular vesicles.

Published 2022 in Glycoconj J, 39: 197-205

Reference contains 8 structures

NCBI Taxonomy ID	Scientific Name
9913	Bos taurus
9615	Canis familiaris
60711	Cercopithecus sabaeus
93934	Coturnix japonica
10026	Cricetinae
9031	Gallus gallus
9606	Homo sapiens
9542	Macaca fuscata
9544	Macaca mulatta
10090	Mus musculus
9986	Oryctolagus cuniculus
9940	Ovis aries
10114	Rattus
9823	Sus scrofa

Consortium for Functional Glycomics (CFG):

carbGlipid_20042_D000

Glyco-CD:

CD77

GlycoEpitope DB:

EP0071

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