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Glycosciences.DB structure entry #134: Lactosylceramide / LacCer

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Format: CarbBank LINUCS


 b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide

Corresponding entries: 55

1 - 5 of 55 entries with matching glycan part

Structure entry #325:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Methyl

no 3d model

NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #1753:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2-propenamide

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #2240:

b-D-Galp-(1-4)-b-D-Glcp-(1-5)-Gln-(1-2)-Tyr-(1-2)-Gly-(1-2)-Gly-(1-2)-Phe-(1-2)-Leu

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #3456:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #5958:

b-D-Galp-(1-4)-b-D-Glcp-(1-3)-Ser-(1-2)-Ile-(1-2)-Lys-(1-2)-Val-(1-2)-Ala-(1-2)-Val

no NMR spectra

literature references

no GlycoMaps

Taxons

lactosylceramide
LacCer
asialo-GM3

glycosphingolipid

General Structure Data

Chemical Formula:	C₄₅H₈₅N₁O₁₃		#C	#H	#O	#N
Molec. Weight:	848		45	85	13	1
# Atoms:	144
# Residues:	3
# Heavy Atoms:	59

Superclasses:

Hex
Hex	2

Residues:

Residue	Count
B-D-GALP	1
B-D-GLCP	1
CERAMIDE	1

PDB references: 1

1 - 1 of 1 PDB entries

PDB ID 5j14: Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3

Description: Putative secreted endoglycosylceramidase

Source: Rhodococcus equi 103S

Experimental method: X-RAY DIFFRACTION

Resolution: 1.915Å

Release date: 2016-04-27

Entry features 2 distinct glycan structures [2 instances].

Literature references: 202

1 - 5 of 202 literature references

Reference #20517

Breimer ME; Säljö K; Barone A; Teneberg S

Glycosphingolipids of human embryonic stem cells.

Published 2017 in Glycoconj. J., 34: 713-723

Reference contains 30 structures

Reference #20522

Schnaar RL; Gerardy-Schahn R; Hildebrandt H

Sialic acids in the brain: gangliosides and polysialic acid in nervous system development, stability, disease, and regeneration.

Published 2014 in Physiol. Rev., 94: 461-518

Reference contains 22 structures

Reference #20480

Wang Z; Wen L; Ma X; Chen Z; Yu Y; Zhu J; Wang Y; Liu Z; Liu H; Wu D; Zhou D; Li Y

High expression of lactotriaosylceramide, a differentiation-associated glycosphingolipid, in the bone marrow of acute myeloid leukemia patients.

Published 2012 in Glycobiology, 22: 930-8

Reference contains 7 structures

Reference #7992

Shirai T; Itonori S; Tai T; Soares MJ; Shiota K; Ogawa T

Ganglioside composition of the rat choriocarcinoma cell line, Rcho-1

Published 1996 in Glycoconj J, 13: 415-421

Reference contains 5 structures

Reference #8139

Fujita N; Suzuki K; Vanier MT; Popko B; Maeda N; Klein A; Henseler M; Sandhoff K; Nakayasu H; Suzuki K

Targeted disruption of the mouse sphingolipid activator protein gene: a complex phenotype, including severe leukodystrophy and wide-spread storage of multiple sphingolipids

Published 1996 in Hum Mol Genet, 5: 711-725

Reference contains 5 structures

NCBI Taxonomy ID	Scientific Name
7588	Asteroidea
9913	Bos taurus
9615	Canis familiaris
93934	Coturnix japonica
10029	Cricetulus griseus
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9544	Macaca mulatta
10090	Mus musculus
9986	Oryctolagus cuniculus
10114	Rattus
9823	Sus scrofa

Glyco-CD:

CD17

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