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Glycosciences.DB structure entry #134: Lactosylceramide / LacCer

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Format: CarbBank LINUCS


 b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide

Corresponding entries: 55

1 - 5 of 55 entries with matching glycan part

Structure entry #325:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Methyl

no 3d model

NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #1753:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2-propenamide

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #2240:

b-D-Galp-(1-4)-b-D-Glcp-(1-5)-Gln-(1-2)-Tyr-(1-2)-Gly-(1-2)-Gly-(1-2)-Phe-(1-2)-Leu

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #3456:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #5958:

b-D-Galp-(1-4)-b-D-Glcp-(1-3)-Ser-(1-2)-Ile-(1-2)-Lys-(1-2)-Val-(1-2)-Ala-(1-2)-Val

no NMR spectra

literature references

no GlycoMaps

Taxons

lactosylceramide
LacCer
asialo-GM3

glycosphingolipid

General Structure Data

Chemical Formula:	C₄₅H₈₅N₁O₁₃		#C	#H	#O	#N
Molec. Weight:	848		45	85	13	1
# Atoms:	144
# Residues:	3
# Heavy Atoms:	59

Superclasses:

Hex
Hex	2

Residues:

Residue	Count
B-D-GALP	1
B-D-GLCP	1
CERAMIDE	1

PDB references: 1

1 - 1 of 1 PDB entries

PDB ID 5j14: Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3

Description: Putative secreted endoglycosylceramidase

Source: Rhodococcus equi 103S

Experimental method: X-RAY DIFFRACTION

Resolution: 1.915Å

Release date: 2016-04-27

Entry features 2 distinct glycan structures [2 instances].

Literature references: 217

1 - 5 of 217 literature references

Reference #21161

Akintayo A; Stanley P

Roles for Golgi Glycans in Oogenesis and Spermatogenesis.

Published 2019 in Front Cell Dev Biol, 7: 98

Reference contains 30 structures

Reference #20740

Dunn TM; Tifft CJ; Proia RL

A perilous path: the inborn errors of sphingolipid metabolism.

Published 2019 in J. Lipid Res., 60: 475-483

Reference contains 9 structures

Reference #21159

Silsirivanit A; Phoomak C; Teeravirote K; Wattanavises S; Seubwai W; Saengboonmee C; Zhan Z; Inokuchi JI; Suzuki A; Wongkham S

Overexpression of HexCer and LacCer containing 2-hydroxylated fatty acids in cholangiocarcinoma and the association of the increase of LacCer (d18:1-h23:0) with shorter survival of the patients.

Published 2019 in Glycoconj. J., 36: 103-111

Reference contains 4 structures

Reference #20758

Pshezhetsky AV; Ashmarina M

Keeping it trim: roles of neuraminidases in CNS function.

Published 2018 in Glycoconj. J., 35: 375-386

Reference contains 10 structures

Reference #21199

Nakayama H; Nagafuku M; Suzuki A; Iwabuchi K; Inokuchi JI

The regulatory roles of glycosphingolipid-enriched lipid rafts in immune systems.

Published 2018 in FEBS Lett., 592: 3921-3942

Reference contains 13 structures

NCBI Taxonomy ID	Scientific Name
7588	Asteroidea
9913	Bos taurus
9615	Canis familiaris
93934	Coturnix japonica
10029	Cricetulus griseus
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9544	Macaca mulatta
10090	Mus musculus
9986	Oryctolagus cuniculus
10114	Rattus
9823	Sus scrofa

Glyco-CD:

CD17

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