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Glycosciences.DB structure entry #134: Lactosylceramide / LacCer

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Format: CarbBank LINUCS


 b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide

Corresponding entries: 55

1 - 5 of 55 entries with matching glycan part

Structure entry #325:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Methyl

no 3d model

NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #1753:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2-propenamide

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #2240:

b-D-Galp-(1-4)-b-D-Glcp-(1-5)-Gln-(1-2)-Tyr-(1-2)-Gly-(1-2)-Gly-(1-2)-Phe-(1-2)-Leu

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #3456:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #5958:

b-D-Galp-(1-4)-b-D-Glcp-(1-3)-Ser-(1-2)-Ile-(1-2)-Lys-(1-2)-Val-(1-2)-Ala-(1-2)-Val

no NMR spectra

literature references

no GlycoMaps

Taxons

lactosylceramide
LacCer
asialo-GM3

glycosphingolipid

General Structure Data

Chemical Formula:	C₄₅H₈₅N₁O₁₃		#C	#H	#O	#N
Molec. Weight:	848		45	85	13	1
# Atoms:	144
# Residues:	3
# Heavy Atoms:	59

Superclasses:

Hex
Hex	2

Residues:

Residue	Count
B-D-GALP	1
B-D-GLCP	1
CERAMIDE	1

PDB references: 1

1 - 1 of 1 PDB entries

PDB ID 5j14: Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3

Description: Putative secreted endoglycosylceramidase

Source: Rhodococcus equi 103S

Experimental method: X-RAY DIFFRACTION

Resolution: 1.915Å

Release date: 2016-04-27

Entry features 2 distinct glycan structures [2 instances].

Literature references: 231

1 - 5 of 231 literature references

Reference #21966

Plasma membrane glycosphingolipid signaling: a turning point.

Published 2022 in Glycoconj J, 39: 99-105

Reference contains 3 structures

Reference #21991

Jin C; Teneberg S

Characterization of novel nonacid glycosphingolipids as biomarkers of human gastric adenocarcinoma.

Published 2022 in J Biol Chem, 298: 101732

Reference contains 18 structures

Reference #21973

Inokuchi JI; Nagafuku M

Gangliosides in T cell development and function of mice.

Published 2022 in Glycoconj J, 39: 229-238

Reference contains 9 structures

Reference #21974

Iwabuchi K; Nakayama H; Hanafusa K

Lactosylceramide-enriched microdomains mediate human neutrophil immunological functions via carbohydrate-carbohydrate interaction.

Published 2022 in Glycoconj J, 39: 239-246

Reference contains 2 structures

Reference #21778

Giussani P; Prinetti A; Tringali C

The Role of Sphingolipids in Cancer Immunotherapy.

Published 2021 in Int J Mol Sci, 22:

Reference contains 11 structures

NCBI Taxonomy ID	Scientific Name
7588	Asteroidea
9913	Bos taurus
9615	Canis familiaris
93934	Coturnix japonica
10029	Cricetulus griseus
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9544	Macaca mulatta
10090	Mus musculus
9986	Oryctolagus cuniculus
10114	Rattus
9823	Sus scrofa

Glyco-CD:

CD17

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