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Glycosciences.DB structure entry #134: Lactosylceramide / LacCer

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Format: CarbBank LINUCS


 b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide

Corresponding entries: 55

1 - 5 of 55 entries with matching glycan part

Structure entry #325:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Methyl

no 3d model

NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #1753:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2-propenamide

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #2240:

b-D-Galp-(1-4)-b-D-Glcp-(1-5)-Gln-(1-2)-Tyr-(1-2)-Gly-(1-2)-Gly-(1-2)-Phe-(1-2)-Leu

no 3d model

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #3456:

b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol

no NMR spectra

literature references

no GlycoMaps

Taxons

Structure entry #5958:

b-D-Galp-(1-4)-b-D-Glcp-(1-3)-Ser-(1-2)-Ile-(1-2)-Lys-(1-2)-Val-(1-2)-Ala-(1-2)-Val

no NMR spectra

literature references

no GlycoMaps

Taxons

lactosylceramide
LacCer
asialo-GM3

glycosphingolipid

General Structure Data

Chemical Formula:	C₄₅H₈₅N₁O₁₃		#C	#H	#O	#N
Molec. Weight:	848		45	85	13	1
# Atoms:	144
# Residues:	3
# Heavy Atoms:	59

Superclasses:

Hex
Hex	2

Residues:

Residue	Count
B-D-GALP	1
B-D-GLCP	1
CERAMIDE	1

PDB references: 1

1 - 1 of 1 PDB entries

PDB ID 5j14: Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3

Description: Putative secreted endoglycosylceramidase

Source: Rhodococcus equi 103S

Experimental method: X-RAY DIFFRACTION

Resolution: 1.915Å

Release date: 2016-04-27

Entry features 2 distinct glycan structures [2 instances].

Literature references: 212

1 - 5 of 212 literature references

Reference #20740

Dunn TM; Tifft CJ; Proia RL

A perilous path: the inborn errors of sphingolipid metabolism.

Published 2019 in J. Lipid Res., 60: 475-483

Reference contains 9 structures

Reference #20758

Pshezhetsky AV; Ashmarina M

Keeping it trim: roles of neuraminidases in CNS function.

Published 2018 in Glycoconj. J., 35: 375-386

Reference contains 10 structures

Reference #20853

Rybová J; Kuchar L; Hulková H; Asfaw B; Dobrovolný R; Sikora J; Havlícek V; Škultéty L; Ledvinová J

Specific storage of glycoconjugates with terminal α-galactosyl moieties in the exocrine pancreas of Fabry disease patients with blood group B.

Published 2018 in Glycobiology, 28: 382-391

Reference contains 5 structures

Reference #20746

Demina EP; Pierre WC; Nguyen ALA; Londono I; Reiz B; Zou C; Chakraberty R; Cairo CW; Pshezhetsky AV; Lodygensky GA

Persistent reduction in sialylation of cerebral glycoproteins following postnatal inflammatory exposure.

Published 2018 in J Neuroinflammation, 15: 336

Reference contains 8 structures

Reference #20517

Breimer ME; Säljö K; Barone A; Teneberg S

Glycosphingolipids of human embryonic stem cells.

Published 2017 in Glycoconj. J., 34: 713-723

Reference contains 30 structures

NCBI Taxonomy ID	Scientific Name
7588	Asteroidea
9913	Bos taurus
9615	Canis familiaris
93934	Coturnix japonica
10029	Cricetulus griseus
9685	Felis catus
9031	Gallus gallus
9606	Homo sapiens
9544	Macaca mulatta
10090	Mus musculus
9986	Oryctolagus cuniculus
10114	Rattus
9823	Sus scrofa

Glyco-CD:

CD17

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