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Glycosciences.DB structure entry #134: Lactosylceramide / LacCer
b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Ceramide
[][CERAMIDE]{[(1+1)][B-D-GLCP]{[(4+1)][B-D-GALP]{}}}
1 - 5 of 55 entries with matching glycan part
Structure entry #325:
b-D-Galp-(1-4)-b-D-Glcp-(1-1)-Methyl
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 13C: 1 |
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 : 9 |
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Taxons |
Structure entry #1753:
b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2-propenamide
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: 2 |
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Taxons |
Structure entry #2240:
b-D-Galp-(1-4)-b-D-Glcp-(1-5)-Gln-(1-2)-Tyr-(1-2)-Gly-(1-2)-Gly-(1-2)-Phe-(1-2)-Leu
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: 1 |
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Taxons |
Structure entry #3456:
b-D-Galp-(1-4)-b-D-Glcp-(1-1)-2R-amino-Octadec-4E-en-1,3S-diol
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: 1 |
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Taxons |
Structure entry #5958:
b-D-Galp-(1-4)-b-D-Glcp-(1-3)-Ser-(1-2)-Ile-(1-2)-Lys-(1-2)-Val-(1-2)-Ala-(1-2)-Val
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: 1 |
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Taxons |
- lactosylceramide
- LacCer
- asialo-GM3
- glycosphingolipid
| Chemical Formula: | C45H85N1O13 | #C | #H | #O | #N | |
| Molec. Weight: | 848 | 45 | 85 | 13 | 1 | |
| # Atoms: | 144 | |||||
| # Residues: | 3 | |||||
| # Heavy Atoms: | 59 | |||||
Superclasses:
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Residues:
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PDB references: 11 - 1 of 1 PDB entries
PDB ID 5j14:
Crystal structure of endoglycoceramidase I from Rhodococ-cus equi in complex with GM3
Description: Putative secreted endoglycosylceramidase
Source: Rhodococcus equi 103S
Experimental method: X-RAY DIFFRACTION
Resolution: 1.915Å
Release date: 2016-04-27
Entry features 2 distinct glycan structures [2 instances].
Literature references: 2231 - 5 of 223 literature references
Reference #21338
Ramos RI; Bustos MA; Wu J; Jones P; Chang SC; Kiyohara E; Tran K; Zhang X; Stern SL; Izraely S; Sagi-Assif O; Witz IP; Davies MA; Mills GB; Kelly DF; Irie RF; Hoon DSB
Upregulation of Cell Surface GD3 Ganglioside Phenotype is Associated with Human Melanoma Brain Metastasis.
Published 2020 in Mol Oncol, :
Reference contains 5 structures
Reference #21588
Jennemann R; Kaden S; Volz M; Nordström V; Herzer S; Sandhoff R; Gröne HJ
Gangliosides modulate insulin secretion by pancreatic beta cells under glucose stress.
Published 2020 in Glycobiology, 30: 722-734
Reference contains 5 structures
Reference #21592
Sugawara S; Takayanagi M; Honda S; Tatsuta T; Fujii Y; Ozeki Y; Ito J; Sato M; Hosono AM
Catfish egg lectin affects influx and efflux rates of sunitinib in human cervical carcinoma HeLa cells.
Published 2020 in Glycobiology, 30: 802-816
Reference contains 3 structures
Reference #20740
Dunn TM; Tifft CJ; Proia RL
A perilous path: the inborn errors of sphingolipid metabolism.
Published 2019 in J. Lipid Res., 60: 475-483
Reference contains 9 structures
Reference #21159
Silsirivanit A; Phoomak C; Teeravirote K; Wattanavises S; Seubwai W; Saengboonmee C; Zhan Z; Inokuchi JI; Suzuki A; Wongkham S
Overexpression of HexCer and LacCer containing 2-hydroxylated fatty acids in cholangiocarcinoma and the association of the increase of LacCer (d18:1-h23:0) with shorter survival of the patients.
Published 2019 in Glycoconj. J., 36: 103-111
Reference contains 4 structures
| NCBI Taxonomy ID | Scientific Name |
| 7588 | Asteroidea |
| 9913 | Bos taurus |
| 9615 | Canis familiaris |
| 93934 | Coturnix japonica |
| 10029 | Cricetulus griseus |
| 9685 | Felis catus |
| 9031 | Gallus gallus |
| 9606 | Homo sapiens |
| 9544 | Macaca mulatta |
| 10090 | Mus musculus |
| 9986 | Oryctolagus cuniculus |
| 10114 | Rattus |
| 9823 | Sus scrofa |
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