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Glycosciences.DB structure entry #1133: LewisB tetrasaccharide (beta-anomeric form)
a-L-Fucp-(1-4)+
|
b-D-GlcpNAc
|
a-L-Fucp-(1-2)-b-D-Galp-(1-3)+
[][B-D-GLCPNAC]{[(3+1)][B-D-GALP]{[(2+1)][A-L-FUCP]{}}[(4+1)][A-L-FUCP]{}}
RES
1b:b-dglc-HEX-1:5
2s:n-acetyl
3b:b-dgal-HEX-1:5
4b:a-lgal-HEX-1:5|6:d
5b:a-lgal-HEX-1:5|6:d
LIN
1:1d(2+1)2n
2:1o(3+1)3d
3:3o(2+1)4d
4:1o(4+1)5d
<?xml version="1.0" encoding="UTF-8"?>
<sugar version="1.0">
<residues>
<basetype id="1" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dglc-HEX-1:5">
<stemtype id="1" type="dglc" />
</basetype>
<substituent id="2" name="n-acetyl" />
<basetype id="3" anomer="b" superclass="hex" ringStart="1" ringEnd="5" name="b-dgal-HEX-1:5">
<stemtype id="1" type="dgal" />
</basetype>
<basetype id="4" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-lgal-HEX-1:5|6:d">
<stemtype id="1" type="lgal" />
<modification type="d" pos_one="6" />
</basetype>
<basetype id="5" anomer="a" superclass="hex" ringStart="1" ringEnd="5" name="a-lgal-HEX-1:5|6:d">
<stemtype id="1" type="lgal" />
<modification type="d" pos_one="6" />
</basetype>
</residues>
<linkages>
<connection id="1" parent="1" child="2">
<linkage id="1" parentType="d" childType="n">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="2" parent="1" child="3">
<linkage id="2" parentType="o" childType="d">
<parent pos="3" />
<child pos="1" />
</linkage>
</connection>
<connection id="3" parent="3" child="4">
<linkage id="3" parentType="o" childType="d">
<parent pos="2" />
<child pos="1" />
</linkage>
</connection>
<connection id="4" parent="1" child="5">
<linkage id="4" parentType="o" childType="d">
<parent pos="4" />
<child pos="1" />
</linkage>
</connection>
</linkages>
</sugar>

1 - 5 of 7 entries with matching glycan part

a-L-Fucp-(1-4)+
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b-D-GlcpNAc-(1-9)-9-hydroxy-Nonanoate-(1-1)-Methyl
|
a-L-Fucp-(1-2)-b-D-Galp-(1-3)+
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Taxons: 1 |

a-L-Fucp-(1-4)+
|
b-D-GlcpNAc-(1-O)-<BSA>
|
a-L-Fucp-(1-2)-b-D-Galp-(1-3)+
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Taxons |

a-L-Fucp-(1-4)+
|
b-D-GlcpNAc-(1-7)-benzyl
|
a-L-Fucp-(1-2)-b-D-Galp-(1-3)+
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Taxons |

a-L-Fucp-(1-4)+
|
b-D-GlcpNAc-(1-1)-Methyl
|
a-L-Fucp-(1-2)-b-D-Galp-(1-3)+
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Taxons |

a-L-Fucp-(1-4)+
|
b-D-GlcpNAc-(1-9)-9-hydroxy-Nonanoate
|
a-L-Fucp-(1-2)-b-D-Galp-(1-3)+
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Taxons |
- Lewis B (Show) (Search Database)
Chemical Formula: | C26H45N1O19 | #C | #H | #O | #N | |
Molec. Weight: | 675 | 26 | 45 | 19 | 1 | |
# Atoms: | 91 | |||||
# Residues: | 4 | |||||
# Heavy Atoms: | 46 |
Superclasses:
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Residues:
|
1 - 3 of 3 PDB entries

PDB ID 4opo:
Crystal structure of P domain from norovirus strain Saga4 in complex with HBGA type Leb (tetraglycan)
Description: VP1
Source: Norovirus Hu/GII-4/Kumamoto5/2006/JP
Experimental method: X-RAY DIFFRACTION
Resolution: 1.4Å
Release date: 2014-12-17
Entry features 1 distinct glycan structures [2 instances].

PDB ID 4ops:
Crystal structure of P domain from norovirus strain Farmington Hills 2004 in complex with HBGA type Leb (tetraglycan)
Description: Major capsid protein
Source: Norovirus Hu/GII.4/Farmington Hills/2004/USA
Experimental method: X-RAY DIFFRACTION
Resolution: 1.76Å
Release date: 2014-12-17
Entry features 1 distinct glycan structures [1 instances].

PDB ID 4gwj:
His 62 mutant of the lectin binding domain of Lectinolysin complexed with Lewis b
Description: Platelet aggregation factor Sm-hPAF
Source: Streptococcus mitis
Experimental method: X-RAY DIFFRACTION
Resolution: 1.6Å
Release date: 2012-11-21
Entry features 1 distinct glycan structures [1 instances].
1 - 5 of 50 literature references

Reference #21957
Montesino B; Steenackers A; Lozano JM; Young GD; Hu N; Sackstein R; Chandler KB
Identification of α1,2-fucosylated signaling and adhesion molecules in head and neck squamous cell carcinoma.
Published 2022 in Glycobiology, 32: 441-455
Reference contains 4 structures

Reference #21814
Roderer D; Bröcker F; Sitsel O; Kaplonek P; Leidreiter F; Seeberger PH; Raunser S
Glycan-dependent cell adhesion mechanism of Tc toxins.
Published 2020 in Nat Commun, 11: 2694
Reference contains 13 structures

Reference #21286
van Leeuwen SS
Challenges and Pitfalls in Human Milk Oligosaccharide Analysis.
Published 2019 in Nutrients, 11:
Reference contains 50 structures

Reference #21136
Alibay I; Burusco KK; Bruce NJ; Bryce RA
Identification of Rare Lewis Oligosaccharide Conformers in Aqueous Solution Using Enhanced Sampling Molecular Dynamics.
Published 2018 in J Phys Chem B, 122: 2462-2474
Reference contains 6 structures

Reference #21745
Corfield AP
The Interaction of the Gut Microbiota with the Mucus Barrier in Health and Disease in Human.
Published 2018 in Microorganisms, 6: 78
Reference contains 36 structures
1 - 2 of 2 literature references from PDB entries

Reference #19039
Singh BK; Leuthold MM; Hansman GS
Human noroviruses' fondness for histo-blood group antigens.
Published 2015 in J. Virol., 89: 2024-40

Reference #18359
Lawrence SL; Feil SC; Holien JK; Kuiper MJ; Doughty L; Dolezal O; Mulhern TD; Tweten RK; Parker MW
Manipulating the Lewis antigen specificity of the cholesterol-dependent cytolysin lectinolysin.
Published 2012 in Front Immunol, 3: 330
NCBI Taxonomy ID | Scientific Name |
9534 | Cercopithecus aethiops |
9606 | Homo sapiens |
10090 | Mus musculus |
9986 | Oryctolagus cuniculus |
Consortium for Functional Glycomics (CFG):
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