| This site provides databases and bioinformatics tools for glycobiology and glycomics. |
News12 Mar 2010: Glycosciences.de is back online!Two years after the unexpectected death of Willi von der Lieth the Molecular Modeling Group at the German Cancer Research Center was closed for good. Therefore, the glycosciences.de server had to be relocated. It is now hosted at the University of Gießen.The relocation of the server has posed a number of problems, many of which should be solved by now. If you still encounter any problems such as dead links or missing connections, please let us know by e-mail to Thomas Lütteke. Some server restarts might be necessary in the near future to fix further problems. Therefore, if the server is not accessible within the next few weeks, please try again later. |
BackgroundThe human genome seems to encode for not more than 30,000 to 40,000 proteins. A major challenge is to understand how posttranslational events, such as glycosylation, affect the activities and functions of these proteins in health and disease. The importance of protein glycosylation is becoming widely realized through studies on protein folding, protein localization and trafficking, protein solubility, biological half-life as well as studies on cell-cell interactions. The progressing Glycomics projects will dramatically accelerate the understanding of the roles of carbohydrates in cell communication and lead to novel therapeutic approaches for treatment of human disease. The MIT's magazine of innovation (January 21 2003) has identified Glycomics as one of the top ten technologies that will change the future. To support the upcoming Glycomics projects we focus our research activities on the development of bioinformatic tools and databases for glycobiology. |
Many of the applications have been developed with financial support of the 'Subject oriented networks' program of the German Research Council DFG. |